Michael Houghton: Difference between revisions
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'''Michael Houghton''' is a British scientist, who along with [[Qui-Lim Choo]], [[George Kuo]] and Daniel W Bradley, co-discovered [[Hepatitis C]] in 1989. He is currently Li Ka Shing Professor of Virology, Canada Excellence Research Chair in Virology, and professor in the Department of Medical Microbiology and Immunology at the [[University of Alberta]].<ref>{{cite web|url=http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php|title=MMI Faculty - Michael Houghton, PhD|accessdate=13 January 2014}}</ref> |
'''Michael Houghton''' is a British scientist, who along with [[Qui-Lim Choo]], [[George Kuo]] and Daniel W Bradley, co-discovered [[Hepatitis C]] in 1989. He is currently Li Ka Shing Professor of Virology, Canada Excellence Research Chair in Virology, director of the Li Ka Shing Applied Virology Institute, and professor in the Department of Medical Microbiology and Immunology at the [[University of Alberta]].<ref>{{cite web|url=http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php|title=MMI Faculty - Michael Houghton, PhD|accessdate=13 January 2014}}</ref> |
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After graduating with a degree in Biological Sciences from the [[University of East Anglia]] in 1972 and a PhD in Biochemistry from [[King's College London]] in 1977, Houghton joined [[G. D. Searle & Company]] before moving to [[Chiron Corporation]] in 1982.<ref name="ref904913078">{{cite book|url=http://books.google.co.uk/books?id=n5P696E7T0wC&pg=PA344&dq=dr+Michael+Houghton&hl=en&sa=X&ei=gW7IUq69IImO7AbepoG4CQ&ved=0CDkQ6AEwAQ#v=onepage&q=dr%20Michael%20Houghton&f=false|title=Liver Cirrhosis and Its Development - Google Books|publisher=books.google.co.uk|accessdate=2014-01-12}}</ref> It was at Chiron that Houghton together with colleagues [[Qui-Lim Choo]] and George Kuo, and D.W. Bradley from the [[Centers for Disease Control and Prevention]] first discovered [[Hepatitis C]]. He also discovered the [[Hepatitis D]] [[genome]].<ref>{{cite journal|last=Wang|first=KS |author2=Choo, QL |author3=Weiner, AJ |author4=Ou, JH |author5=Najarian, RC |author6=Thayer, RM |author7=Mullenbach, GT |author8=Denniston, KJ |author9=Gerin, JL |author10=Houghton, M|title=Structure, sequence and expression of the hepatitis delta (delta) viral genome|journal=Nature|date=9 October 1986|volume=323|issue=6088|pages=508–14|pmid=3762705|doi=10.1038/323508a0}}</ref> |
After graduating with a degree in Biological Sciences from the [[University of East Anglia]] in 1972 and a PhD in Biochemistry from [[King's College London]] in 1977, Houghton joined [[G. D. Searle & Company]] before moving to [[Chiron Corporation]] in 1982.<ref name="ref904913078">{{cite book|url=http://books.google.co.uk/books?id=n5P696E7T0wC&pg=PA344&dq=dr+Michael+Houghton&hl=en&sa=X&ei=gW7IUq69IImO7AbepoG4CQ&ved=0CDkQ6AEwAQ#v=onepage&q=dr%20Michael%20Houghton&f=false|title=Liver Cirrhosis and Its Development - Google Books|publisher=books.google.co.uk|accessdate=2014-01-12}}</ref> It was at Chiron that Houghton together with colleagues [[Qui-Lim Choo]] and George Kuo, and D.W. Bradley from the [[Centers for Disease Control and Prevention]] first discovered [[Hepatitis C]]. He also discovered the [[Hepatitis D]] [[genome]].<ref>{{cite journal|last=Wang|first=KS |author2=Choo, QL |author3=Weiner, AJ |author4=Ou, JH |author5=Najarian, RC |author6=Thayer, RM |author7=Mullenbach, GT |author8=Denniston, KJ |author9=Gerin, JL |author10=Houghton, M|title=Structure, sequence and expression of the hepatitis delta (delta) viral genome|journal=Nature|date=9 October 1986|volume=323|issue=6088|pages=508–14|pmid=3762705|doi=10.1038/323508a0}}</ref> |
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Revision as of 20:03, 22 February 2016
Michael Houghton | |
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| Alma mater | University of East Anglia (BSc) King's College London (PhD) |
| Known for | Hepatitis C Hepatitis D |
| Awards | Robert Koch Prize 1993 Lasker Award 2000 Gairdner Foundation International Award 2013 (declined) |
| Scientific career | |
| Fields | Microbiology Virology |
| Institutions | University of Alberta Chiron Corporation |
| Thesis | RNA Polymerases and Transcription in the Chicken Oviduct (1977) |
| Website | Michael Houghton, PhD |
Michael Houghton is a British scientist, who along with Qui-Lim Choo, George Kuo and Daniel W Bradley, co-discovered Hepatitis C in 1989. He is currently Li Ka Shing Professor of Virology, Canada Excellence Research Chair in Virology, director of the Li Ka Shing Applied Virology Institute, and professor in the Department of Medical Microbiology and Immunology at the University of Alberta.[1]
After graduating with a degree in Biological Sciences from the University of East Anglia in 1972 and a PhD in Biochemistry from King's College London in 1977, Houghton joined G. D. Searle & Company before moving to Chiron Corporation in 1982.[2] It was at Chiron that Houghton together with colleagues Qui-Lim Choo and George Kuo, and D.W. Bradley from the Centers for Disease Control and Prevention first discovered Hepatitis C. He also discovered the Hepatitis D genome.[3]
In 2013, Houghton's team at the University of Alberta showed that a vaccine derived from a single strain of Hepatitis C was effective against all strains of the virus. The vaccine is currently in clinical trials.[4]
He was awarded the Robert Koch Prize in 1993, and the Lasker Award in 2000. In 2013 he become the first person to decline the $100,000 Gairdner Foundation International Award stating "I felt that it would be unfair of me to accept this award without the inclusion of two colleagues, Dr. Qui-Lim Choo and Dr. George Kuo".[5][6]
References
- ^ "MMI Faculty - Michael Houghton, PhD". Retrieved 13 January 2014.
- ^ Liver Cirrhosis and Its Development - Google Books. books.google.co.uk. Retrieved 2014-01-12.
- ^ Wang, KS; Choo, QL; Weiner, AJ; Ou, JH; Najarian, RC; Thayer, RM; Mullenbach, GT; Denniston, KJ; Gerin, JL; Houghton, M (9 October 1986). "Structure, sequence and expression of the hepatitis delta (delta) viral genome". Nature. 323 (6088): 508–14. doi:10.1038/323508a0. PMID 3762705.
- ^ Law, JL; Chen, C; Wong, J; Hockman, D; Santer, DM; Frey, SE; Belshe, RB; Wakita, T; Bukh, J; Jones, CT; Rice, CM; Abrignani, S; Tyrrell, DL; Houghton, M. (March 19, 2013). "A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans". PLoS One. 8 (3). doi:10.1371/journal.pone.0059776. PMID 23527266.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ "World-renowned virologist named recipient of Gairdner Award". March 22, 2013. Retrieved 13 January 2014.
- ^ Boesveld, Sarah (20 March 2013). "Edmonton scientist turns down $100,000 'baby Nobel' because it shut out colleagues". Retrieved 13 January 2014.
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