Irreversible agonist: Difference between revisions
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== Examples == |
== Examples == |
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* [[Oxymorphazone]] |
* [[Oxymorphazone]] |
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* [[Metaphit]] |
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== See also == |
== See also == |
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Revision as of 19:45, 23 October 2016
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An irreversible agonist is a type of agonist that binds permanently to a receptor in such a manner that the receptor is permanently activated. It is distinct from a mere (reversible) agonist in that the association of an agonist to a receptor is reversible, whereas the binding of an irreversible agonist to a receptor is, at least in theory, irreversible. Oxymorphazone is an example of an irreversible agonist.[1] In practice, the distinction may be more a matter of degree, in which the binding affinity of an irreversible agonist is some orders of magnitude greater than that of an agonist.
Examples
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