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Subacute lymphocytic thyroiditis can only be diagnosed correctly by taking a [[radioactive iodine uptake test]] (RAIU) test.<ref name=afp/><ref name=raiu>[http://www.webmd.com/a-to-z-guides/radioactive-iodine-uptake-test Description of Radioactive Iodine Uptake Test, WebMD.com, August 14, 2008]</ref>
Subacute lymphocytic thyroiditis can only be diagnosed correctly by taking a [[radioactive iodine uptake test]] (RAIU) test.<ref name=afp/><ref name=raiu>[http://www.webmd.com/a-to-z-guides/radioactive-iodine-uptake-test Description of Radioactive Iodine Uptake Test, WebMD.com, August 14, 2008]</ref>


During the hyperthyroid phase, iodine uptake is increased, while during the hypothyroid phase, uptake is decreased.<ref name=nih>[http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000388.htm NIH Medline Plus]</ref>
During both the hyperthyroid and hypothyroid phases, radioiodine uptake is decreased.<ref name=nih>[http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000388.htm NIH Medline Plus]</ref>


This situation contrasts greatly with the elevated iodine uptake found in patients with [[Graves' disease]].<ref name=afp/>
This situation contrasts greatly with the elevated iodine uptake found in patients with [[Graves' disease]].<ref name=afp/>

Revision as of 17:35, 22 February 2018

Subacute lymphocytic thyroiditis is a form of thyroiditis that is also known as silent thyroiditis or painless thyroiditis. Subacute lymphocytic thyroiditis may occur at any age and is more common in females.

A variant of subacute lymphocytic thyroiditis occurs postpartum, postpartum thyroiditis. Both of these entities can be considered subtypes of Hashimoto's thyroiditis and have an autoimmune basis. Anti-thyroid antibodies are common in all three and the underlying histology is similar. [1][2] This disorder should not be confused with de Quervain's thyroiditis which is another form of subacute thyroiditis.

Symptoms

Subacute lymphocytic thyroiditis features a small goiter without tenderness. This condition tends to have a phase of hyperthyroidism followed by a return to a euthyroid state, and then a phase of hypothyroidism, followed again by a return to the euthyroid state. The time span of each phase can vary; however, each phase usually lasts 2–3 months.[1]

Diagnosis

Subacute lymphocytic thyroiditis can only be diagnosed correctly by taking a radioactive iodine uptake test (RAIU) test.[1][3]

During both the hyperthyroid and hypothyroid phases, radioiodine uptake is decreased.[4]

This situation contrasts greatly with the elevated iodine uptake found in patients with Graves' disease.[1]

Treatment

Treatment is based on symptoms. Beta-blockers relieve rapid heart rate and excessive sweating during the hyperthyroid phase.[4]

References

This template is no longer used; please see Template:Endocrine pathology for a suitable replacement