Mark van der Giezen: Difference between revisions
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van der Giezen investigates adaptations of microbial [[eukaryotes]] to life under [[anoxia]], or low oxygen. He discovered mitochondrial remnants ([[mitosomes]]) in the human intestinal parasite ''[[Giardia intestinalis]]'' <ref>Nature (2003) 426: 172-176</ref>, an organism until then considered to be one of the most primitive eukaryotes. This discovery called for re-assessment of the evolution of [[mitochondria]]. |
van der Giezen investigates adaptations of microbial [[eukaryotes]] to life under [[anoxia]], or low oxygen. He discovered mitochondrial remnants ([[mitosomes]]) in the human intestinal parasite ''[[Giardia intestinalis]]'' <ref>Nature (2003) 426: 172-176</ref>, an organism until then considered to be one of the most primitive eukaryotes. This discovery called for re-assessment of the evolution of [[mitochondria]]. |
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van der Giezen's research has demonstrated that several unusual organelles are in fact mitochondria <ref>EMBO J (2002) 21: 572-579; Mol Biol Evol (2003) 20: 1051-1061</ref>. More recently, he has conducted large dataset analyses of microbial eukaryotes <ref>Curr Biol (2008) 18: 580-585</ref>. His current work includes next-generation sequencing projects, and he is involved in several eukaryotic genome projects. He annotated and curated 10% of the ''[[Emiliania huxleyi]]'' genome <ref>Nature (2013) 499: 209-213</ref> and other genomes are currently in progress including crustacean and fish parasite genomes. Most recently, van der Giezen has been involved in sequencing the genome of the most common microbial eukaryote found in human intestines <ref>PLoS Biology (2017) 15(9): e2003769</ref>. He uses large-scale [[RNA-Seq]] analyses for [[protists]] that are difficult to culture <ref>Curr Biol (2014) 24: 1176–1186</ref>. |
van der Giezen's research has demonstrated that several unusual organelles are in fact mitochondria <ref>EMBO J (2002) 21: 572-579; Mol Biol Evol (2003) 20: 1051-1061</ref>. More recently, he has conducted large dataset analyses of microbial eukaryotes <ref>Curr Biol (2008) 18: 580-585</ref>. His current work includes next-generation sequencing projects, and he is involved in several eukaryotic genome projects. He annotated and curated 10% of the ''[[Emiliania huxleyi]]'' genome <ref>Nature (2013) 499: 209-213</ref> and other genomes are currently in progress including crustacean and fish parasite genomes. Most recently, van der Giezen has been involved in sequencing the genome of the most common microbial eukaryote found in human intestines <ref>PLoS Biology (2017) 15(9): e2003769</ref>. He uses large-scale [[RNA-Seq]] analyses for [[protists]] that are difficult to culture <ref>Curr Biol (2014) 24: 1176–1186</ref>. |
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== Life == |
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Mark van der Giezen was born on 24th May 1968. His primary and secondary education was in Assen, The Netherlands. He studied Biology, with graduate level Molecular Genetics & Immunology, at The [[University of Groningen]], remaining to obtain a PhD in 1997 in Mathematical and Natural Sciences, supervised by Professor [[Rudolf Prins]], in the Department of Microbiology. His PhD thesis was entitled ''The evolutionary origin of fungal hydrogenosomes''. |
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From October 1997 to March 2002 van der Giezen was an [[EMBO]] Fellow in the group of Prof. [[Martin Embley]] at the Department of Zoology, [[The Natural History Museum]], London, UK. |
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From April 2002 to October 2004 he was a post-doctoral researcher in the group of Dr. [[Jorge Tovar]] at the School of Biological Sciences, [[Royal Holloway, University of London]], UK. |
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In November 2004 van der Giezen became Lecturer in Microbiology in the School of Biological Sciences, [[Queen Mary, University of London]], UK. |
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In September 2007 moved to the [[University of Exeter]], UK, as Senior Lecturer in Evolutionary Biochemistry. |
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== References == |
== References == |
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Mark van der Giezen is Senior Lecturer (Associate Professor) in Evolutionary Biochemistry, Biosciences, University of Exeter, UK.
van der Giezen investigates adaptations of microbial eukaryotes to life under anoxia, or low oxygen. He discovered mitochondrial remnants (mitosomes) in the human intestinal parasite Giardia intestinalis [1], an organism until then considered to be one of the most primitive eukaryotes. This discovery called for re-assessment of the evolution of mitochondria.
van der Giezen's research has demonstrated that several unusual organelles are in fact mitochondria [2]. More recently, he has conducted large dataset analyses of microbial eukaryotes [3]. His current work includes next-generation sequencing projects, and he is involved in several eukaryotic genome projects. He annotated and curated 10% of the Emiliania huxleyi genome [4] and other genomes are currently in progress including crustacean and fish parasite genomes. Most recently, van der Giezen has been involved in sequencing the genome of the most common microbial eukaryote found in human intestines [5]. He uses large-scale RNA-Seq analyses for protists that are difficult to culture [6].
Life
Mark van der Giezen was born on 24th May 1968. His primary and secondary education was in Assen, The Netherlands. He studied Biology, with graduate level Molecular Genetics & Immunology, at The University of Groningen, remaining to obtain a PhD in 1997 in Mathematical and Natural Sciences, supervised by Professor Rudolf Prins, in the Department of Microbiology. His PhD thesis was entitled The evolutionary origin of fungal hydrogenosomes.
From October 1997 to March 2002 van der Giezen was an EMBO Fellow in the group of Prof. Martin Embley at the Department of Zoology, The Natural History Museum, London, UK.
From April 2002 to October 2004 he was a post-doctoral researcher in the group of Dr. Jorge Tovar at the School of Biological Sciences, Royal Holloway, University of London, UK.
In November 2004 van der Giezen became Lecturer in Microbiology in the School of Biological Sciences, Queen Mary, University of London, UK.
In September 2007 moved to the University of Exeter, UK, as Senior Lecturer in Evolutionary Biochemistry.