Jean E. Schaffer
Jean Elise Schaffer, MD | |
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 Jean Elise Schaffer | |
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Jean Elise Schaffer is an American physician-scientist. She is a Senior Investigator at the Joslin Diabetes Center, where she also serves as Associate Research Director, and she is Professor of Medicine at Harvard Medical School. Her work focuses on fundamental mechanisms of metabolic stress responses and the pathophysiology of diabetes complications.
Education
Schaffer completed an A.B. in biochemistry, phi beta kappa and magna cum laude from Harvard College. As an undergraduate, she performed her thesis work with Richard I. Morimoto Ph.D. in the laboratory of Matthew Meselson, Ph.D. She earned an M.D., cum laude from Harvard Medical School [1]. Schaffer completed an internship and residence in medicine at Brigham and Women's Hospital, and clinical and research fellowship in cardiology at Beth Israel Hospital. She carried out postdoctoral training with Harvey F. Lodish, PhD at the Whitehead Institute at Massachusetts Institute of Technology, during which time she cloned the first member of the fatty acid transport protein family [1].
Career
In 1995, Schaffer joined the faculty at Washington University School of Medicine in St Louis. She rose through the ranks and was appointed as the inaugural Virginia Minnich Distinguished Professor of Medicine [1]. In addition to leading a laboratory focused on metabolic disease research, she directed the NIDDK-funded Diabetes Research Center at Washington University from 2008-2019. Her laboratory discovered that disruption of specific small nucleolar RNAs protects against lipid-induced cell death and alters metabolism, work that has provided a new understanding of how nutrient signals influence cellular homeostasis through non-coding RNAs [1]. Schaffer’s contributions to the fields of lipid metabolism and metabolic stress have been recognized by American Society for Clinical Investigation, American Association for the Advancement of Science, Association of American Physicians and American Society for Biochemistry and Molecular Biology (5, 6). In 2019, Schaffer was recruited to the Joslin Diabetes Center at Harvard Medical School (7)..[1]
Awards and Honors
1993 Katz Basic Science Research Prize, American Heart Association
2003 American Society for Clinical investigation
2008 Fellow of the American Association for the Advancement of Science
2012 Association American of Physicians
2017 Harold Rifkin Award, Albert Einstein College of Medicine
2018 Robert P. Hebbel Award, University of Minnesota
2020 Avanti Award in Lipids, American Society for Biochemistry and Molecular Biology
References
- Living people
- Harvard College alumni
- Harvard Medical School alumni
- Harvard Medical School of Medicine faculty
- Washington University School of Medicine faculty
- American cardiologists
- Women cardiologists
- 20th-century American physicians
- 21st-century American physicians
- 20th-century American scientists
- 21st-century American scientists
- 20th-century American women physicians
- 21st-century American women physicians
- 20th-century American women scientists
- 21st-century American women scientists
- Fellows of the American Association for the Advancement of Science