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Andrea Baccarelli

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Andrea Baccarelli
M.D., M.P.H., Ph.D
BornDecember 6, 1970
Italy
NationalityItalian
CitizenshipAmerican, Italian (Dual citizenship)
EducationPhD, 2003, University of Milan

MPH, 2000, University of Turin

MD, 1995, University of Perugia
Scientific career
FieldsEnvironmental health sciences, epigenetics, mitochondriomics, and computational epigenomics
InstitutionsNational Cancer Institute’s Division of Cancer Epidemiology and Genetics (2000-2004)

Universita' degli Studi di Milano (2004-2010)

Harvard School of Public Health (2010-2016)

Columbia University Mailman School of Public Health (2016-Present)

Andrea Baccarelli (born December 6, 1970) is an American Italian epigeneticist and clinical endocrinologist, known for his academic contributions in the field of epigenetics, mitochondriomics, and computational epigenomics, with a research focus on investigating the impact of environmental exposures on human health. He serves as Professor and Chair of the Department of Environmental Health Sciences at the Columbia University Mailman School of Public Health.[1][2]

Education and career

Baccarelli obtained his Master of Science in Epidemiology from the University of Turin, Italy, in 2000 and a Ph.D. in Molecular Epidemiology from the Universita' degli Studi di Milano, Italy, in 2003.[3]

He completed his residency in endocrinology at the University of Milan and his postdoctoral fellowship at the National Cancer Institute’s Division of Cancer Epidemiology and Genetics (2000-2004).[4]

Baccarelli has served since 2016 as the Environmental Health Sciences Department Chair and the Director of the Laboratory of Precision Environmental Biosciences at the Columbia University Mailman School of Public Health.[5][6] Prior to joining Columbia University in 2016, he was the Mark and Catherine Winkler Associate Professor of Environmental Epigenetics at the Harvard School of Public Health.[7]

He was elected to the National Academy of Medicine and as President of the International Society of Environmental Epidemiology in 2020.[8]

Scientific work

Baccarelli's research focuses on epigenetic and molecular mechanisms as potential links between human disease burden and exposures to pollutants. His laboratory research activities have a focus on studying the effects of environmental pollutants on health, in particular on a molecular level.

Awards and recognition

Baccarelli was recognized as the “Person of the Year” by the City of Perugia, Italy.[9][10]

Selected publications

  • Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr. 2009 Apr;21(2):243-51.[11]
  • Marioni, R.E., Shah, S., McRae, A.F. et al. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol 16, 25 (2015).[12]
  • Baccarelli, Andrea; Wright, Robert O.; Bollati, Valentina. et al. "Rapid DNA Methylation Changes after Exposure to Traffic Particles".[13]
  • Bollati, Valentina, et al. "Changes in DNA methylation patterns in subjects exposed to low-dose benzene." Cancer research 67.3 (2007): 876-880.[14]
  • Levine, Morgan E., et al. "An epigenetic biomarker of aging for lifespan and healthspan." Aging (Albany NY) 10.4 (2018): 573.[15]

References

  1. ^ "Air pollution spikes may impair older men's thinking, study finds". the Guardian. 2021-05-03. Retrieved 2021-10-21.
  2. ^ ""C'è una relazione tra inquinamento e capacità cognitive"". la Repubblica (in Italian). 2021-05-21. Retrieved 2021-10-21.
  3. ^ "Una vita per la ricerca, Il Baiocco d'oro a Baccarelli". Tuttoggi (in Italian). 2018-08-21. Retrieved 2021-10-22.
  4. ^ "Andrea Baccarelli | Columbia Public Health". www.publichealth.columbia.edu. Retrieved 2021-10-21.
  5. ^ Naish, John. "In the office or dining out — how clean is the air you breathe?". ISSN 0140-0460. Retrieved 2021-10-21.
  6. ^ Oliveira, Alexandra (2020-09-28). "Five environmental policy questions that should be asked in the presidential debates". TheHill. Retrieved 2021-10-21.
  7. ^ Kirkpatrick, Bailey (2016-07-28). "3 Pioneering Epigenetic Labs: Exploring the People and Discoveries that Transcend the Lab Walls". What is Epigenetics?. Retrieved 2021-10-22.
  8. ^ "Five Elected to the National Academy of Medicine". Columbia University Irving Medical Center. 2020-10-16. Retrieved 2021-10-21.
  9. ^ "Perugia consegna il Baiocco d'oro al professor Andrea Baccarelli: «È uno dei nostri figli migliori»". Umbria24.it (in Italian). Retrieved 2021-10-22.
  10. ^ "Baiocco d'Oro al super professore perugino: "Oggi la città premia uno dei suoi figli migliori"". PerugiaToday (in Italian). Retrieved 2021-10-22.
  11. ^ Baccarelli, Andrea; Bollati, Valentina (2009). "Epigenetics and environmental chemicals". Current Opinion in Pediatrics. 21 (2): 243–251. doi:10.1097/MOP.0b013e32832925cc. ISSN 1040-8703.
  12. ^ Marioni, Riccardo E; Shah, Sonia; McRae, Allan F; Chen, Brian H; Colicino, Elena; Harris, Sarah E; Gibson, Jude; Henders, Anjali K; Redmond, Paul; Cox, Simon R; Pattie, Alison (2015). "DNA methylation age of blood predicts all-cause mortality in later life". Genome Biology. 16 (1): 25. doi:10.1186/s13059-015-0584-6. ISSN 1474-760X. PMC 4350614. PMID 25633388.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  13. ^ Baccarelli, Andrea; Wright, Robert O.; Bollati, Valentina; Tarantini, Letizia; Litonjua, Augusto A.; Suh, Helen H.; Zanobetti, Antonella; Sparrow, David; Vokonas, Pantel S.; Schwartz, Joel (2009). "Rapid DNA Methylation Changes after Exposure to Traffic Particles". American Journal of Respiratory and Critical Care Medicine. 179 (7): 572–578. doi:10.1164/rccm.200807-1097OC. ISSN 1073-449X. PMC 2720123. PMID 19136372.{{cite journal}}: CS1 maint: PMC format (link)
  14. ^ Bollati, Valentina; Baccarelli, Andrea; Hou, Lifang; Bonzini, Matteo; Fustinoni, Silvia; Cavallo, Domenico; Byun, Hyang-Min; Jiang, Jiayi; Marinelli, Barbara; Pesatori, Angela C.; Bertazzi, Pier A. (2007-02-01). "Changes in DNA Methylation Patterns in Subjects Exposed to Low-Dose Benzene". Cancer Research. 67 (3): 876–880. doi:10.1158/0008-5472.CAN-06-2995. ISSN 0008-5472.
  15. ^ Levine, Morgan E.; Lu, Ake T.; Quach, Austin; Chen, Brian H.; Assimes, Themistocles L.; Bandinelli, Stefania; Hou, Lifang; Baccarelli, Andrea A.; Stewart, James D.; Li, Yun; Whitsel, Eric A. (2018-04-18). "An epigenetic biomarker of aging for lifespan and healthspan". Aging. 10 (4): 573–591. doi:10.18632/aging.101414. ISSN 1945-4589. PMC 5940111. PMID 29676998.{{cite journal}}: CS1 maint: PMC format (link)
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