GMC
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The initialism GMC can mean either:
- GMC, a division of General Motors Corporation formerly named "GMC Truck"
- Greater Middlesex Confrence, The Central NJ Football Confrence home of Piscataway,Monroe,New Brunswick and Middlesex
- Green Mountain College, a liberal arts college in Poultney, Vermont
- Game Maker Community, the GMC is the official forum of Game Maker - a game creation tool
- Gebrüder Märklin & Cie, a German model railway manufacturer, see Märklin
- German Mouse Clinic
- General Medical Council (of the United Kingdom)
- Gene Mapping Centre
- Genetically Modified Crop
- Georgia Military College in Milledgeville, Georgia
- Giant Molecular Cloud
- Global Motion Compensation used by video codecs
- GNU Midnight Commander, a file manager for Unix-like systems
- Greater Manchester County
- Generalized Method of Cells, a micromechanics theory
- Groupe mixte de Combat n°1, unit of the Free French Air Force in the UK.
- Gmodcentral, a Garry's Mod community