Oxalobacter aliiformigenes
| Oxalobacter aliiformigenes | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Betaproteobacteria |
| Order: | Burkholderiales |
| Family: | Oxalobacteraceae |
| Genus: | Oxalobacter |
| Species: | O. aliiformigenes
|
| Binomial name | |
| Oxalobacter aliiformigenes Chmiel et al, 2022
| |
| Type strain | |
| Oxalobacter aliiformigenes Va3T | |
Oxalobacter aliiformigenes is a Gram negative, non-spore-forming, oxalate-degrading anaerobic bacterium that was first isolated from human fecal samples.[1] O. aliiformigenes is believed to have roles in calcium oxalate kidney stone disease because of its unique ability to utilize oxalate as its primary carbon source.[2]
Taxonomy
Oxalobacter aliiformigenes was originally thought to be a subgroup of Oxalobacter formigenes based on fatty acid profile, 16S ribosomal RNA sequencing, and DNA probes specific to the oxc (oxalyl-CoA decarboxylase) gene and frc (formyl-CoA transferase).[1][3][4][5]. However, full genomes were sequenced and based on average nucleotide identity calculation, digital DNA-DNA hybridization, and phylogenetic tree analyses, O. aliiformigenes was determined to be a distinct species.[6]
Antibiotic resistance and susceptibility
Oxalobacter aliiformigenes demonstrates in vitro resistance to amoxicillin, ampicillin, ceftriaxone, cephalexin, streptomycin, and vancomycin; and in vitro sensitivity to clarithromycin, clindamycin, ciprofloxacin, doxycycline, gentamicin, and tetracycline.[7][8]
Genome
The genome of O. formigenes has been sequenced by multiple researchers and is revealed to be 2.2 – 2.4 Mb with a G+C content of 50.9 - 51.5%.[6]
References
- ^ a b Allison MJ, Dawson KA, Mayberry WR, Foss JG (February 1985). "Oxalobacter formigenes gen. nov., sp. nov.: oxalate-degrading anaerobes that inhabit the gastrointestinal tract". Archives of Microbiology. 141 (1): 1–7. doi:10.1007/BF00446731. PMID 3994481. S2CID 10709172.
- ^ Duncan, Sylvia H.; Richardson, Anthony J.; Kaul, Poonam; Holmes, Ross P.; Allison, Milton J.; Stewart, Colin S. (2002). "Oxalobacter formigenes and Its Potential Role in Human Health". Applied and Environmental Microbiology. 68 (8): 3841–3847. doi:10.1128/AEM.68.8.3841-3847.2002. ISSN 0099-2240. PMC 124017. PMID 12147479.
- ^ Jensen, N.S.; Allison, M.J. (1994). "Studies on the diversity among anaerobic oxalate-degrading bacteria now in the species Oxalobacter formigenes, abstr. I-12". Abstracts of the 94th General Meeting of the American Society for Microbiology 1994. Washington, D.C., USA: American Society for Microbiology. p. 255.
- ^ Sidhu, H; Allison, M; Peck, A B (1997). "Identification and classification of Oxalobacter formigenes strains by using oligonucleotide probes and primers". Journal of Clinical Microbiology. 35 (2): 350–353. doi:10.1128/jcm.35.2.350-353.1997. ISSN 0095-1137. PMC 229578. PMID 9003594.
- ^ Garrity, George M.; Bell, Julia A.; Lilburn, Timothy (2005), Brenner, Don J.; Krieg, Noel R.; Staley, James T. (eds.), "Class II. Betaproteobacteria class. nov.", Bergey’s Manual® of Systematic Bacteriology, Boston, MA: Springer US, pp. 575–922, doi:10.1007/978-0-387-29298-4_2, ISBN 978-0-387-24145-6, retrieved 2022-11-10
- ^ a b Chmiel, John A.; Carr, Charles; Stuivenberg, Gerrit A.; Venema, Robertson; Chanyi, Ryan M.; Al, Kait F.; Giguere, Daniel; Say, Henry; Akouris, Polycronis P.; Domínguez Romero, Sergio Ari; Kwong, Aaron; Tai, Vera; Koval, Susan F.; Razvi, Hassan; Bjazevic, Jennifer (2022-12-21). "New perspectives on an old grouping: The genomic and phenotypic variability of Oxalobacter formigenes and the implications for calcium oxalate stone prevention". Frontiers in Microbiology. 13: 1011102. doi:10.3389/fmicb.2022.1011102. ISSN 1664-302X. PMC 9812493. PMID 36620050.
- ^ Duncan SH, Richardson AJ, Kaul P, Holmes RP, Allison MJ, Stewart CS (August 2002). "Oxalobacter formigenes and its potential role in human health". Applied and Environmental Microbiology. 68 (8): 3841–3847. Bibcode:2002ApEnM..68.3841D. doi:10.1128/AEM.68.8.3841-3847.2002. PMC 124017. PMID 12147479.
- ^ Lange JN, Wood KD, Wong H, Otto R, Mufarrij PW, Knight J, et al. (June 2012). "Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics". Urology. 79 (6): 1286–1289. doi:10.1016/j.urology.2011.11.017. PMC 3569510. PMID 22656407.