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This is an old revision of this page, as edited by Rfts (talk | contribs) at 04:49, 8 October 2008. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Introduction

Tuberculosis (TB) of the spine (Pott’s disease) is the most common site of bone infection in TB; hips and knees are also often affected. The lower thoracic and upper lumbar vertebrae are the areas of the spine most often affected.

Pathogenesis Of Pott’s Disease

Pott’s disease results from haematogenous spread of tuberculosis from other sites, often pulmonary. The infection then spreads from two adjacent vertebrae into the adjoining disc space. If only one vertebra is affected, the disc is normal, but if two are involved the intervertebral disc, which is avascular, cannot receive nutrients and collapses. The disc tissue dies and is broken down by caseation, leading to vertebral narrowing and eventually to vertebral collapse and spinal damage). A dry soft tissue mass often forms and superinfection is rare. Diagnosis of Pott’s disease Clinical

The disease progresses slowly. Signs and symptoms include:

   * Localised back pain
   * Paravertebral swelling may be seen
   * Systemic signs and symptoms of TB may be present
   * Neurological signs may occur, leading to paraplegia.

Microbiology

   * Needle biopsy of bone or synovial tissue. Numbers of tubercle bacilli present are usually low but are pathognomonic. 
   * Acid-fast stain and culture for Mycobacterium tuberculosis, plus fungi and other pathogens, should be performed.

Imaging

   * Spinal x-ray may not show early disease as 50% of bone mass must be lost for changes to be visible on x-ray. However, plain radiog

A Doll's House

In a Doll's House, consumption of the spine refers to syphillis, not this disease, as it says this in the wikipedia article for a Doll's House, too. Rfts (talk) 04:49, 8 October 2008 (UTC)[reply]

needs template

I navigated here by a template. this needs that template.

done. —Preceding unsigned comment added by 128.125.77.48 (talk) 22:24, 4 November 2007 (UTC)[reply]

what other disease often misdiagnosed as Pott's disease?

My father is diagnosed and treated as such, on his spine L4 and L5, but the bone biopsy culture shows no signs of TB.

Merge suggestion

It seems to me that Spinal Tuberculosis should be merged here. MisfitToys (talk) 20:43, 17 March 2008 (UTC)[reply]

Corrections/Cleanup Needed

Someone's been playing a prank with this page. Under Symptoms, "accidental ass explosion" has been inserted, and the fictional Hunchback of Notre Dame's condition is said to be "caused by Robert Pott." Can someone knowledgable about the original wording correct this? —Preceding unsigned comment added by Pwyrdan (talkcontribs) 19:10, 9 July 2008 (UTC)[reply]

Name Change (Pott Disease)

I think that the name ought to be changed to "Pott Disease." Current naming conventions are moving towards removing the apostrophe from disease names. —Preceding unsigned comment added by Slevit1 (talkcontribs) 21:53, 22 July 2008 (UTC)[reply]