Michelle Khine

Michelle Khine is a distinguished scientist and innovator at the University of California, Irvine, the scientific founder of the Shrink nano-technology platform, as well as the Assistant and Founding Professor of the School of Engineering at UC Merced. Michelle Khine is responsible for experimenting with the child hood toy Shrinky Dinks to build microfluidic devices. Michelle's research has enabled technological advances in industries including solar technology, biological research and medical diagnostics.

Michelle Khine is a widely published researcher, with multiple patents grants and honors including the 2009 MIT Technology Review TR 35 Award: Selected as Top 35 Innovator under 35 in the world. Michelle Khine is also on several review committees, most notable being the Center for Scientific Review at the National Institute of Health.

Education

Michelle received her BS in 1999 and MS in 2001, under Dennis Lieu, in Mechanical Engineering from UC Berkeley. Michelle continued her education at UC Berkley and UCSF receiving her PhD in 2005, under Luke P Lee, in Bioengineering. While in graduate school, she worked at Sandia National Labs as a MESA Fellow as well as co-founded Fluxion Biosciences (San Francisco, Ca), which was based on her dissertation work.

Selected Honors and Awards

In November 2000 Michelle Khine and fellow collegiate Melodie Metzger received the World Speed Record using the UC Berkeley Human Powered Vehicle (Bearacuda), reaching a top record speed of 38.4 mhp in the Women’s Low Altitude Tandem; not only setting the tandem record but besting the female sprint record for single rider vehicles, 600/200m Sprint. U.C. Berkeley Bearacuda becomes the Fastest Collegiate Human Powered Vehicle in History

In September 2009, Michelle was honored with the 2009 MIT Technology Review TR 35 Award: Selected as Top 35 Innovator under 35 in the world.TR35 2009 Young Innovator

Selected peer-reviewed publications (in chronological order). * = corresponding author

Ionescu-Zanetti C., Blatz A., Khine, M.*, “Electrophoresis-Assisted Single-Cell Electroporation for Efficient Intracellular Delivery”, Biomed Microdevices. 10(1):113-6, 2008.

Grimes A., Breslauer D.N, Long M., Pegan J., Lee L.P., Khine, M.*, “Shrinky-Dink Microfluidics: Rapid Generation of Deep and Rounded Patterns”, Lab on a Chip. 8(1):170-2, 2008. Highlighted in Chemical and Engineering News, Chemical Technology, on the Front page of American Chemical Society Homepage, (acs.org), front page of Lab on a Chip Homepage, and Wired. Most accessed paper January 2008. Lab on a Chip

Chen, C.S., Breslauer, D.N., Luna, J.I., Grimes, A., Chin, W.C., Lee, L.P, Khine M.,* “Shrinky Dink Microfluidics: 3-D Polystyrene Chips,” Lab on a Chip, 8, 622–624, 2008. Highlighted in Nature Medicine (May 2008). Lab on a Chip

Nyugen, D.,Pegan, J., Sa, S., McCloskey,K.E., Manilay, J.O., Khine,*,”Shrink-Induced Honeycomb Microwells for Uniform Embryoid Bodies” accepted to Lab on a Chip. Lab on a Chip

External Links

UC Merced Faculty: Michelle Khine
UC Irvine Faculty: Michelle Khine
MIT 2009 TR35: Michelle Khine
Toaster oven helps researchers toy with microfluidics
Shrink Nanotechnologies Team