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Protein subfamily

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Protein subfamily is a level of protein classification, especially protein 3D structures. It is under protein Family. Protein family in SCOP (Structural Classification of Proteins) means the members are all related evolutionarily and they share very similar structures with functional similarities. Protein Subfamily is when the Family members share the same interaction interfaces and interaction partners. This more strict criterion forces that all the subfamily members have to share functionally related.


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