Microcoria

Microcoria is a congenital disease in which the pupils of the subject are narrower than 2mm in diameter. Microcoria is associated with juvenile-onset glaucoma. It is also associated with Pierson syndrome chararacterized by microcoria and congenital nephrotic syndrome. Mutations at chromosomal locus 3p21 in the Laminin Beta 2 gene which encodes an essential glomerular basement membrane protein. (Zenker et al 2004)

It is also part of the known manifestations of a born infant to a mother suffering from uncontrolled hyperglycemia. Other symptoms include transposition of great vessels, respiratory distress secondary to surfactant defect, sacral agensis, jitteriness, irritability, and lethargy due to rebound fetal hypoglycemia.

See also

• Miosis