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This is an old revision of this page, as edited by 129.180.166.53 (talk) at 03:39, 11 June 2012 (→‎From acetyl CoA... not faty acid breakdown?: new section). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Acetoacetate not a ketone?

The three ketone bodies are acetoacetate, beta-hydroxybutyrate and acetone. (The first two are not technically ketones according to IUPAC nomenclature, but the third is.)

I see how beta-hydroxybutyrate isn't a true ketone because it lacks a ketone functional group, but it certainly seems that carbon three of acetoacetate forms part of a ketone functional group. I've updated the page pending further discussion. Also, according to ketone bodies, acetoacetate is a true ketone body. --David Iberri (talk) 22:52, 24 March 2007 (UTC)[reply]

HMG-CoA error

189.42.228.115 (talk) 21:29, 13 July 2008 (UTC) On the grafic, β-hydroxy-β-methylglutaryl-CoA (HMG-CoA) is decompose in acetoacetate and CoASH, but it´s impossible because 2 carbons disapear and has lack of energy. In french page, the liase forms Acetyl-Coa, that is more plausible.[reply]

Reference

I really need the reference for the statement that the ketegonesis is initiated "if the amounts of acetyl-CoA generated in fatty-acid β-oxidation challenge the processing capacity of the TCA cycle or if activity in the TCA cycle is low due to low amounts of intermediates such as oxaloacetate" - does anyone know where I can find this? i tried all the references listed without luck. I would really much appreciate it!

My email is cduun07@student.aau.dk

thanks! — Preceding unsigned comment added by 130.225.198.198 (talk) 11:49, 4 April 2012 (UTC)[reply]

From acetyl CoA... not faty acid breakdown?

In "types of ketone bodies" it states, "each of these compounds is synthesized from acetyl CoA", yet at the intro it says "fatty acid breakdown". How about just say acetyl CoA -> ketone, is ketogenesis? 129.180.166.53 (talk) 03:39, 11 June 2012 (UTC)[reply]