GAIN domain

GPS containing protein module involved in autocatalytic cleavage of adhesion-GPCRs. ^[1] ^[2] ^[3]

GPCR-Autoproteolsis INducing (GAIN) domain, rat latrophilin 4DLQ mediates autocatalytic cleavage of adhesion GPCRs

References

^ Araç, D (2012 Feb 14). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". The EMBO journal. 31 (6): 1364–78. PMID 22333914. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ Lin, HH (2004 Jul 23). "Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif". The Journal of biological chemistry. 279 (30): 31823–32. PMID 15150276. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ Chang, GW (2003 Jul 17). "Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif". FEBS letters. 547 (1–3): 145–50. PMID 12860403. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)