Jump to content

Aprotinin

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by AED (talk | contribs) at 00:14, 4 June 2006 (If we let in one ambulance chaser, then we have to let them all in.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Aprotinin (Trasylol®, Bayer) is an injection used to reduce bleeding and clotting during heart surgery. Aprotinin is a chemical in the body responsible for breaking down certain proteins in the blood which prevents blood clot formation and thus increase bleeding. Thus, aprotinin limits bleeding by eliminating the breakdown of clots, and can be used to prevent excessive blood loss during surgery.

Side effects

Aprotinin doubles a patient's risk of kidney failure, heart failure, and heart attack in heart bypass patients as well as the number of patients needing kidney dialysis. A research by Ischemia Research and Education Foundation and the McSPI Research Group, led by Dennis T. Mangano, advises replacing Aprotinin by other, safer generic drugs.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Aprotinin&oldid=56744477"