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Talk:5-HTTLPR

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This is an old revision of this page, as edited by 2602:306:bded:c710:3c2d:e249:b47e:5501 (talk) at 15:13, 16 November 2013. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

why would the S/S polymorphism be associated with depression if it infact causes more serotonin in the synaptic cleft? It acts like an SSRI? What is the mechanism of this relationship?

Technically beyond the scope of a wikipedia talk page, but the "serotonergic model" of depression is not foolproof. Other neurotransmitters also take part. For example, enhancing dopamine can also successfully treat depression.

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