Talk:Amoxicillin

I think this is not good practice to list or create articles about brand names (proprietary names). They come and go. Besides in different countries the same drug by the same manufacturer is sold under different brand names.
There are exceptions of course we definitely should have articles about : Viagra,Valium,Prozac and possibly Rohypnol (date-rape drug ?).

Can we ask the administrators to issue the official policy on brand names of pharmaceuticals ?

There is not yet an official policy, but personally I don't have a problem with it. If it's a subject some people want to know about, we do our readers a disservice not to cover it just because of some misplaced concern about "commercialism". Let's face it; people won't search for "Diazepam"; they'll search for "Valium", and expect an article on it. Of course, that article should simply say that "Valium" is a trademarked brand name for Diazepam, and then desribe what Diazepam is and what it does. I think all should be treated similarly: mention the brand name and the generic name, and use the generic name in most of the text. --LDC

I think we can create redirects from lesser known brand names to generic names pages but we should stick to generic (or better INN - international names) throughout the text of articles possibly giving brand names at the top or in brackets.

Intermediate sensitivity

I removed the unsourced edit that doubling the dose also helps with intermediately sensitive organisms. Although it makes sense, such an assertion needs support from the literature before our readers start taking their tables at twice the rate :-) JFW | T@lk 08:35, 9 October 2005 (UTC)[reply]

That brings up an interesting question... I worked as a pharmacy tech, and regularly sorted amoxil to patients. I was just wondering.... if a doctor prescribed a week-long dose of amoxil (should be 10 days, but I hear 7 days is long enough), and the patient, upon reading something like that, took a double-dose, that would mean they would run out of the drug within 3 days, correct?

In that case, if the bacteria isn't susceptible, would that not cause drug resistance?

Nevermind, I seem to have answered my own question... heh. Kareeser 02:01, 14 December 2005 (UTC)[reply]

Potassium Clavulanate not Clavulanic Acid

I used to make this stuff and I know that Clavulanic Acid is never used in Amox mixes but is changed into Potassium Clavulanate (see the product pages for Augmentin at SmithKilne Beecham). The actual conversion process is :- Streptomyces clavuligerus - Clavulanic acid - Tertiary butylamine salt of Clavulanic acid (tBA) - Potassium Clavulanate. I have been correcting the pages to show the actual chemical used. Tmd63 10:59, 16 February 2006 (UTC)[reply]

I have just checked in the British National Formulary and technicaly you are correct, however the common usage of the terms is as it appears in medical formularies and even more commonly on a doctor's prescriptions and the labels patients read on their medicine bottles. With many drugs the official names miss out on the details on the particular salt used, eg 'Erythromycin' is usally prescribed as the single word, the particular salt is not relevant to its spectrum of antibiotic activity and only rarely is it necessary to distinguish the 'stearate' from the 'ethyl succinate' forms. The correct (at least in the UK) pharmacy & medical term to use is Clavulanic acid, similary the amoxicillin used in Co-amoxiclav is prescribed just as 'Amoxicillin', yet in oral form the trihydrate is used and that for injection uses the sodium salt. To quote from the BNF, which sets out the use of terms:

"Co-amoxiclav A mixture of amoxicillin (as the trihydrate or as the sodium salt) and clavulanic acid (as potassium clavulanate)..."

I'll therefore revert back, but add the details of the forms used to Amoxicillin, Co-amoxiclav, Clavulanic acid and Potassium Clavulanate (which incidentally is wrong in its specification of only being mixed with the trihydrate form of Amoxicillin)David Ruben ^Talk 00:13, 17 February 2006 (UTC)[reply]

Side Effects

Some side affects may include nose bleeds shitting out the mouth and puking on controllably