Jump to content

Calicheamicin

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Mxpule (talk | contribs) at 22:28, 29 October 2006. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)

Calicheamicin is an antibiotic derived from organism [Micromonospora echinospora]. It was isolatied originally from a rock collected in [Waco, Texas] by a hiking [Scripps Institute] chemist.

It is highly toxic and has found pharmacological use as a conjugate in antibody cancer therapeutics (e.g. [Gemtuzumab]).

References

http://www.scripps.edu/newsandviews/e_20010226/nicolaou3.html J Antibiot (Tokyo). 1989 Jul;42(7):1070-87.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Calicheamicin&oldid=84499691"