Stanton Cohn
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Dr. Stanton Cohn (August 25, 1920, Chicago, Illinois – April 28, 2008, Portland, Oregon) was an expert in osteoporosis and a medical researcher at Brookhaven National Lab.
Life
Cohn was born in Chicago, Illinois in 1920 to Harry and Ethel Cohn, parents of Eastern European Jewish heritage. He married Sylva May on March 20, 1949 and had five children. He served in the United States Army from June 1943 until April 1946 working as a biochemist in the 203rd General Hospital Division.[1]
After the war, he attended University of Chicago, graduating with a B.A. and M.S. in 1946. He later attended University of California Berkeley where he received his Ph.D. in 1952 in physiology and radiobiology. His thesis was "The Effects of Ionizing Radiation on the Growth and Metabolism of Bone."[2] He worked at the Naval Research Laboratory from 1950 to 1970.[3] He rose to become the head of the Medical Physics Division in 1970, a position that he held until his retirement in 1987. [3]
Cohn was a pioneer in the study of non-invasive measurement of calcium and other elements in the human body. He was one of the early developers of in vivo neutron activation analysis for body composition in 1971.[4] Along with J.J. Kehayias, K.J. Ellis and J.H. Weinlein he "established the first inelastic scattering facility for estimating total body carbon and oxygen in 1987."[5]
At Brookhaven National Lab, he led a group using a Whole-body_counting [6] [7] to identify and measure radioactive material in the body. He later was part of a team that was among the first to recognize that nuclear fallout from test sites might have local health implications.[1] Cohn was an important member of the team that returned to the Marshall Islands after the United States government performed nuclear testing [8] , to aid the Marshallese people and to continue monitoring, in 1959, 1961, 1974 and 1977.[9] [10] [11] [12] [13]
In subsequent years, he expanded his work to study the effects of cadmium, mercury and other harmful elements on workers in the smelting and mining industries. [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30]
Selected Publications
- “Effects of Total Body X-Irradiation on Blood Coagulation in the Rat,” S.H. Cohn from Blood, The Journal of Hematology, Vol. 7, No. 2, Feb, 1952 http://bloodjournal.hematologylibrary.org/content/7/2
- “The Effects of Ionizing Radiation on the Growth and Metabolism of Bone,” S.H. Cohn, Ph.D. Thesis: University of California, 1952
- “Nature and Extent of Internal Radioactive Contamination of Human Beings, Plants and Animals Exposed to Fallout,” S.H. Cohn, R.W. Rinehart, J.K. Gong, J.S. Robertson, W.L. Milne, US Naval Radiological Defense Laboratory, TR-86, Mar, 1954 https://apps.dtic.mil/docs/citations/AD0617134
- “Radiotoxicity Resulting from Exposure to Fallout Simulant: The Metabolism of an Inhaled and Ingested Simulant of Fallout Produced by Land-base Nuclear Detonation,” S.H. Cohn, W.R. Lane, J.K. Gone, and W.L. Milne, US Naval Radiological Defense Labe TR-118, Jan, 1957 https://www.osti.gov/opennet/servlets/purl/16030232-MbeTHc/16030232.pdf
- “Trabecular and Cortical Bone Composition,” J.K. Gong, J.S. Arnold and S.H. Cohn, From The Anatomical Record, Vol 149, Issue 3, pp 325-331, Jul 1964 and USNRDL-TR-460-1960 http://onlinelibrary.wiley.com/doi/10.1002/ar.1091490303/abstract
- “In-vivo Measurement by the Whole-body Gamma Spectrometer of the Degradation Rate of I-131 Labeled Normal Albumin.” S.W. Lippincott, S.H. Cohn, J.S. Robertson, L.E. Farr. Lab Invest. 10: 481, 1961 http://www.ncbi.nlm.nih.gov/pubmed/13762578
- “Use of a Portable Whole-Body Counter to Measure Internal Contamination in a Fallout-Exposed Population,” S.H. Cohn, R.A. Conard, E.A. Gusmano, J.S. Robertson, From Health Physics Vol 9, pp15-23, Pergamon Press 1963 http://journals.lww.com/health-physics/Abstract/1963/01000/Use_of_a_Portable_Whole_body_Counter_to_Measure.4.aspx
- “Evaluation of Plutonium Exposures in Man,” J.S. Robertson and S.H. Cohn, From Health Physics 10: 373, 1964 http://journals.lww.com/health-physics/Abstract/1964/06000/Evaluation_of_Plutonium_Exposures_in_Man.1.aspx
- “Metabolism of Zinc-65 in Man,” H. Spencer, B. Rosoff, A. Feldstein, S.H. Cohn, E.A. Gusmano, From Radiation Research, Vol. 24, No. 3, pp 432-445, Mar 1965 http://www.jstor.org/pss/3571635
- “Strontium and Calcium Skeletal Discrimination Determined by Compartmental Analysis,” S.H. Cohn, S.R. Bozzo, J.E. Jesseph, C. Constantinides, E.A. Gusmano, J.S. Robertson, From Journal of Applied Physiology, vol. 21, No. 1, pp 67-72, Jan 1966 http://www.ncbi.nlm.nih.gov/pubmed/5903946
- “Calculation of Radiation Dose from Thorotrast Using Whole-body Gamma-ray Spectral Data,” S.H. Cohn, E.A. Gusmano And J.S. Robertson, From Annals of the New York Academy of Sciences, Vol 145, Article 3, pp 608-622, Dec 1967 http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1967.tb50262.x/abstract
- “In-Vivo Neutron Activation Analysis of Calcium in Man,” S.H. Cohn, C.S. Dombrowski and R.G. Fairchild, From International Journal of Applied Radiation and Isotopes, Vol 21, pp127-137, 1970, Pergamon Press http://www.ncbi.nlm.nih.gov/pubmed/5424615
- “Pharmacokinetics of Halothane in Man: A Novel Approach,” L.C. Mark, I.C. Geddes, J.R. Scherrer, C.S. Dombrowski and S.H. Cohn, From International Journal of Applied Radiation Isotopes, Vol. 22, pp171-175, 1971, Pergamon Press http://www.ncbi.nlm.nih.gov/pubmed/4995791
- “Treatment of Osteoporosis with Calcitonin,” S. Wallach, J. Aloia and S. Cohn, From Seminars in Drug Treatment, Vol 2, No 1 (Summer), pp. 21-25, 1972
- “Body Composition Changes in Children Receiving Human Growth Hormone,” P.J Collipp, V. Curti, J. Thomas, R.K. Sharma, V.T. Maddaiah and S.H. Cohn, From Metabolism, vol, 22, No 4, pp 589-595, Apr, 1973 http://www.ncbi.nlm.nih.gov/pubmed/4696903
- “A Multivariate Predictor for Total Body Calcium in Man Based on Activation Analysis,” S.H. Cohn, K.K. Shukla and K.J. Ellis, From Journal of Nuclear Medicine and Biology, Vol 1, pp 131-134, Jun, 1973 https://www.ncbi.nlm.nih.gov/pubmed/4817576
- “Experimental Particle Radiation Therapy in Animal Neoplasia,” S.W. Lippincott, J.L. Montour, J.D. Wilson, S. Cohn and R. E. Flora, From Acta Radiologica Therapy Physics Biology, vol 12, Fasc. 6, pp 541-551, Dec, 1973 http://www.ncbi.nlm.nih.gov/pubmed/4787172
- “Correlation of Radial Bone Mineral Content with Total-Body Calcium in Various Metabolic Disorders,” S.H. Cohn, K.J. Ellis, I. Zanzi, J.M. Letteri and J. Aloia, From International Conference on Bone Mineral Measurement, Chicago, 1973. DHEW Publication No. (NIH) 75-683 (Also BNL-18304) http://www.osti.gov/bridge/purl.cover.jsp?purl=/4405764-OE7KED/
- “Skeletal Turnover and Total Body Elemental Composition During Extended Calcitonin Treatment of Paget’s Disease,” S. Wallach, A Avramides, A. Flores, J. Bellavia and S.H. Cohn, From Metabolism, Vol. 24, No. 6, pp 745-753, Jun 1975 http://www.ncbi.nlm.nih.gov/pubmed/1128238
- “Total Body Potassium and 24-hour Creatinine Excretion in Healthy Males,” W.J. Turner and S. Cohn, From Clinical Pharmacology and Therapeutics, vol, 18, No. 4, pp 405-412, Oct, 1975, http://www.ncbi.nlm.nih.gov/pubmed/1164823
- “Total Body Sodium and Chlorine in Normal Adults,” K.J. Ellis, A. Vaswani, I. Zanzi and S.H. Cohn, From Metabolism, Vol 25, No 6, pp 645-654, Jun, 1976 http://www.ncbi.nlm.nih.gov/pubmed/1272071
- “Effect of Hydrocortisone on Total Body Calcium in Rats,” S. Yasumura, K.J. Ellis and S.H. Cohn, From The Journal of Laboratory and Clinical Medicine, Vol 88, No 5, pp 834-840, Nov, 1976 http://www.ncbi.nlm.nih.gov/pubmed/978046
- “Applications of Neutron Activation Analysis in Nuclear Medicine,” S.H. Cohn and R. Fairchild, From CRC Handbook in Nuclear Medicine, Ed. R.P. Spencer 1, 285-326, 1977
- “Effect of Salmon Calcitonin on Skeletal Mass in Osteoporosis,” S. Wallach, S.H. Cohn, H.L. Atkins, K.J. Ellis, R. Kohberger, J.F. Aloia and I. Zanzi, From Current Therapeutic Research, Vol 22, No 4, pp 556-572, Oct, 1977 https://www.researchgate.net/publication/236533807_Calcitonin_in_the_treatment_of_osteoporosis
- “Medical Applications of In-Vivo Neutron Activation Analysis at Brookhaven National Laboratory,” S.H. Cohn, K.J. ellis, D. Varsky, I. Zanzi and J.F. Aloia, From IAEA, Symposium on Nuclear Activation Techniques in the Life Sciences, Vienna, May 1978. IAEA SM – 227/63, pp 747-761, 1978 http://www.osti.gov/bridge/purl.cover.jsp?purl=/6934724-BCCxrP/
- “In Vivo Neutron Activation Analysis,” S.H. Cohn, From Textbook of Nuclear Medicine: Basic Sciences, A.F.G. Rocha and J.C. Harbert (Eds.) Lea & Febiger, Phil., 1978, pp 394-406 (ISBN: 9780812106305 )
- “Evaluation of the Health Hazard from Inhaled Krypton-85,” S.H. Cohn, K.J. Ellis and H. Susskind, From IAEA Symposium on Biological Implications of Radionuclide Released from Nuclear Industries, Vienna, IAEA-SM-237/46, pp 315-328, 1979 (see also BNL-25813) http://www.osti.gov/bridge/purl.cover.jsp?purl=/6423958-jatTmv/
- “In Vivo Quantification of Body Nitrogen and Body Composition in Normal Subjects and in Cancer Patients for Cancer-Nutrition Studies,” S.H. Cohn, A. Sawitsky, D. Vartsky, S. Yasumura, I. Zanzi and K. Ellis, From Nutrition and Cancer, Vol 2, No 1, pp 67-71, 1980 http://www.ajcn.org/content/35/5/1186.full.pdf
- “Total Body Electrolyte Composition and Distribution of Body Water in Uremia,” B.L Brennan, S. Yasumura, J.M. Letteri and S.H. Cohn, From Kidney International, Vol 17, pp 364-371, 1980 http://www.ncbi.nlm.nih.gov/pubmed/7401456
- “Compartmental Body Composition Based on Total-Body Nitrogen, Potassium, and Calcium,” S.H. Cohn, D. Vartsky, S. Yasumura, A. Sawitsky, I. Zanzi, A. Vaswani and K.J. Ellis, From Am. J. Physiol, Vol 239, pp E524-530, 1980 http://www.ncbi.nlm.nih.gov/pubmed/7446727
- “In Vivo Neutron Activation Analysis: State of the Art and Future Prospects.” S.H. Cohn, Med. Physics 8, 145, 1981. https://www.ncbi.nlm.nih.gov/pubmed/7033755
- “Calcitonin Treatment of Osteoporosis” R. Agrawal, S. Wallach, S.H. Cohn, M. Tessier, R. Verch, M. Hussein and I. Zanzi In Calcitonin 1980 Chemical, Physiological, Pharmocological and Chemical Aspects. Excerpta Medica, Amsterdam, 1981. https://inis.iaea.org/collection/NCLCollectionStore/_Public/12/591/12591952.pdf
- “Changes in Body Composition Following Therapy of Osteoporosis with Methandrostenolone” J.F. Aloia, A. Kapoor, A.N. Vaswani and S.H. Cohn. Metab. 30, 1076-1079, 1981 https://www.ncbi.nlm.nih.gov/pubmed/7026971
- “Comparison of Methods of Estimating Body Fat in Normal Subjects and Cancer Patients” S.H. Cohn, K.J. Ellis, D. Vartsky, A. Sawitsky, W. Gartenhaus, S. Yasumura and A.N. Vaswani. Am. J. Clin. Nutr. 34, 2839-47, 1981. https://www.ncbi.nlm.nih.gov/pubmed/7315785
- “Silicon Measurement in a Lung Phantom by Neutron Inelastic Scattering” K.V. Ettinger, W.D. Morgan, U.J. Miola, D. Vartsky, K.J. Ellis, L. Wielopolski and S.H. Cohn Med. Physics, 9, 550-558, 1982 https://www.ncbi.nlm.nih.gov/pubmed/7110086
- “Container Effects in 56Mn Sources for Iron Determination in the Human Body by NRS Technique” L. Wielopolski, D. Vartsky, D.C. Rorer, P.W. Levy and S.H. Cohn, Nuclear Science Symposium. IEEE Trans. on Nuclear Science, Vol NS-30, No. 1, Feb. 1983 https://ieeexplore.ieee.org/document/4332339
- “The Spectral Shape and Components of Background in in-vivo Prompt Gamma Neutron Activation” D. Vartsky, K.J. Ellis, L. Wielopolski and S.H. Cohn, Nucl. Instr. and Methods 213, 437-446-1983 https://www.sciencedirect.com/science/article/pii/0167508783904398
- “Total Body Phosphorus in Postmenopausal Women” J.F. Aloia, A.N. Vaswani, J.K. Yeh, K.J. Ellis and S.H. Cohn, Minteral and Elect. Metab, 10: 73-76, 1984 https://www.ncbi.nlm.nih.gov/pubmed/6700565
- “A Facility for in-vivo Measurement of Lithium” D. Vartsky, L. Wielopolski, K.J. Ellis and S.H. Cohn, NeuroToxicology 4, 169, 1983 https://www.ncbi.nlm.nih.gov/pubmed/6686306
- “Osteoporosis: How to Prevent the Brittle-bone Disease” W. Smith, S.H. Cohn 1985 ISBN 978-0671552527
- “Nuclear Resonance Scattering Measurement of Human Iron Stores” L. Wielopolski, R. Ancona, D. Vartsky, A. Vaswani, M. Hossey and S.H. Cohn. Med. Phys, 12, 401-404, 1985 https://www.ncbi.nlm.nih.gov/pubmed/4033584
- “In-vivo measurement of Lithium in the Body by a Neutron Activation Analysis Technique” D. Glaros, A. LoMonte, K.J. Ellis, S. Yasumur, R.W. Stoenner and S.H. Cohn, Medical Physics 13, 45-49, 1986 https://www.ncbi.nlm.nih.gov/pubmed/3951408
- “Use of a High Repetition Rate Neutron Generator for in-vivo Body Composition Measurement via Neutron Inelastic Scattering” J.J. Kehayias, K.J. Ellis and S.H. Cohn, Nucl. Instr. & Methods in Phys. Res. B24/25, 1006-1009, N. Holland, Amsterdam 1987 https://inis.iaea.org/search/search.aspx?orig_q=RN:1807203
- “Calcitriol in the Treatment of Post-menopausal Osteoporosis” J.F. Aloia, A.N. Vaswani, J.K. Yeh, K.J. Ellis, S. Yasumura and S.H. Cohn, Am. J. Med, 84, 401-408, 1988 https://www.ncbi.nlm.nih.gov/pubmed/327976
External links
- Cerra, Frances (January 10, 1982). "Elderly Aid in Study of Bone Disease". The New York Times.
- Talan, Jamie (March 25, 1984). "Hope for Osteoporosis Victims". The New York Times.
- https://www.bnl.gov/bnlweb/pubaf/bulletin/obit/Cohn.asp
References
- ^ a b Stanton Cohn, Osteoporosis Expert, Dies at 87
- ^ The Effects of Ionizing Radiation on the Growth and Metabolism of Bone
- ^ a b Human Radiation Studies: Remembering the Early Years page 25/48 footnote 60
- ^ Human Body Composition Second Edition Page 8
- ^ Human Body Composition Second Edition Page 9
- ^ The Scientist, 1987
- ^ Popular Mechanics March 1961 Page 284
- ^ Pacific Proving Grounds
- ^ Residual Contamination of Plants, Animals, Soil and Water of the Marshall Islands One Year Following Operation Castle Fall-out,” R.W. Rinehart, S.H. Cohn, J. Seiler, W. Shipman and J.K. Gong, US Naval Research Defense Laboratory-454, NS 081-001, NM 006-015.04 Aug, 1955.
- ^ “Residual Contamination of Plants, Animals, Soil and Water of the Marshall Islands Two Years Following Operation Castle Fallout,” H.V. Weiss, S.H. Cohn, W.H. Shipman, J.K. Gong, US Naval Radiological Defense Laboratory-455, NS 081-001, Aug, 1956
- ^ “Medical Survey of Rongelap People, March 1958, Four Years After Exposure to Fallout,” R.A. Conard, J.S. Robertson, S.H. Cohn et al. BNL-534 (T-135), 1959
- ^ “Medical Status of Marshall Islanders in 1959, Five Years After Exposure to Fallout Radiation,” R.A. Conard, L.M. Meyer, W.W. Sutow, B.S. Blumberg, A. Lowery, S.H. Cohn et al. From Nuclear Medicine 1: 314-30, Jul 1960
- ^ “Medical Survey of Rongelap People, March 1959, Five and Six Years After Exposure to Fallout,” R.A. Conard, S.H. Cohn et al. BNL-609 (T-179), Sep 1960
- ^ A Facility for in vivo Measurement of Kidney and Liver Cadmium by Neutron Capture Prompt-Gamma Ray Analysis,” D. Vartsky, K.J. Ellis, N.S. Chen and S.H. Cohn, From Phys. Med. & Biology, Vol. 22, No 6, pp 1085-1096, 1977.
- ^ Medical Application of Neutron Capture Gamma-ray Spectroscopy: Measurement of Cadmium and Nitrogen in Living Human Subjects,” D. Vartsky, K.J. Ellis and S.H. Cohn, From 3rd International Symposium on Neutron Capture Gamma-ray Spectroscopy, Brookhaven National Laboratory, pp 785-788, 1978, Ed., R Chrien & W. Kane, Plenum Press, New York (also BNL-24711)
- ^ Cadmium: In-vivo Measurement in Smokers and Nonsmokers,” K.J. Ellis, D. Vartsky, I Zanzi, S.H. Cohn and S. Yasamura, From Science, Vol. 205, pp 323-325, Jul, 1979
- ^ Cadmium in the Environment, Ecological Cycling (Environmental Science and Technology: A Wiley-Interscience Series of Texts and Monographs) (Part 1),” “Global Cadmium Cycle and an Overview of Cadmium in Human Beings,”, pp 12-34, Ed. J.O. Nriagu, J. Wiley and Sons, New York, 1980 (ISBN 9780471064558)
- ^ Critical Concentrations of Cadmium in Human Liver and Kidney Measured by Prompt-Gamma Neutron Activation,” S.H. Cohn, D. Vartsky, S. Yasumura, I. Zanzi and K.J. Ellis, From Cadmium 79. Proc. 2nd Int. Cadmium Conf., Cannes, France, Published by Cadmium Assoc. London and Cadmium Council, New York, p 168-171, 1980 (Also BNL-25707)
- ^ “In-vivo Measurement of Critical Level of Kidney Cadmium: Dose Effect Studies in Cadmium Smelter Workers” K.J. Ellis, W.D. Morgan, I. Zanzi, S. Yasumura, D. Vartsky and S.H. Cohn. 2nd Ann. Environ. Health Conference, Park City, Utah. March, 1980. Am. J. Indust. Med. 1, 339-348, 1980
- ^ “In-vivo Measurement of Cadmium in an Occupationally Exposed Population” K.J. Ellis, W.D. Morgan, S. Yasumura, I. Zanzi and S.H. Cohn. 4th Int. Conf. on Nuclear Methods in Environmental and Energy Researh, Columbia, Missouri, CONF 800433, 388-397, 1980
- ^ “Critical Concentration of Cadmium in Human Renal Cortex (Dose Effect Studies in Cadmium Smelter Workers)” K.J. Ellis, W.D. Morgan, I. Zanzi, S. Yasumura, D. Vartsky and S.H. Cohn, J. Toxicol. & Environ. Health, 7, 691, 1981
- ^ “Calibration of a 238Pu,Be Facility for Partial Body Measurement of Organ Cadmium” W.D. Morgan, K.J. Ellis, D. Vartsky, S. Yasumura and S.H. Cohn. Phys. Med. Biol., 26, 577-590, 1981
- ^ “Metallothionein Excretion in Urine Upon Cadmium Exposure: its Relationship with Liver and Kidney Cadmium” C. Tohyama, Z.A. Shaikh, K.J. Ellis, S.H. Cohn Toxicology. 1981;22(3):181-91.
- ^ “Urinary Metallothionein as a Biological Indicator of Occupational Cadmium Exposure” C. Tohyama, Z.A. Shaikh, K.J. Ellis, S.H. Cohn Cadmium 81, Proc. 3rd Int. Cadmium Conf., Miami, P 180-82, 1981
- ^ “Critical Organ Concentration of Cadmium in Occupationally Exposed Workers” K.J. Ellis, W.D. Morgan, D. Vartsky, I. Zanzi and s.H. Cohn. Cadmium 81, Proc. 3rd Int. Cadmium Conference, Miami, P. 161-166, 1981
- ^ “Hair Cadmium Content: Is it a Biological Indicator of Body Burden of Cadmium for the Occupationally Exposed Worker?” K.J. Ellis, S. Yasumur and S.H. Cohn. Am. J. Indust. Med. 2, 323-330, 1981.
- ^ “Evaluation of Biological Indicators of Body Burden of Cadmium in Humans” K.J. Ellis, S. Yasumura, D. Vartsky and S.H. Cohn, Fund. and Appl. Toxicology 3, 169-174, 1983.
- ^ “In-vivo Monitoring of Heavy Metals in Man: Cadmium and Mercury” K.J. Ellis, D. vartsky, and S.H. Cohn. NeuroToxicology, 4, 164-168, 1983.
- ^ “Dose-response Analysis of Cadmium in Man: Body Burden vs. Kidney Dysfunction” K.J. Ellis, K. Yuen, S. Yasumura and S.H. Cohn, Envir. Res Feb. 1984.
- ^ “Cadmium Inhalation Exposure Estimates: Their Significance with Respect to Kidney and Liver Cadmium Burden” K.J. Ellis, S.H. Cohn, T. Smith. J. Toxicology Environ. Health 15, 173-187, 1985 .
Category:1920 births
Category:2008 deaths
Category:University of Chicago alumni
Category:Deaths from cancer in Oregon