Gypenoside

Gypenosides are triterpenoid saponins and are the main active components of Gynostemma pentaphyllum, a climbing plant in the Cucurbitaceae family.^[1] They have been traditionally used in herbal medicine and have been shown to be effective in the treatment of cardiovascular diseases, although their mechanism of action is unknown.^[2]

Gypenoside A has the chemical structure C₄₆H₇₄O₁₇.^[3]

References

^ Lu, Kung-Wen; Chen, Jung-Chou; Lai, Tung-Yuan; Yang, Jai-Sing; Weng, Shu-Wen; Ma, Yi-Shih; Tang, Nou-Ying; Lu, Pei-Jung; Weng, Jing-Ru; Chung, Jing-Gung (2010-05-01). "Gypenosides Causes DNA Damage and Inhibits Expression of DNA Repair Genes of Human Oral Cancer SAS Cells". In Vivo. 24 (3): 287–291. ISSN 0258-851X. PMID 20555000. Retrieved 2018-07-14.
^ Tanner, MA; Bu, X; Steimle, JA; Myers, PR (1999). "The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum". Nitric Oxide. 3 (5): 359–365. doi:10.1006/niox.1999.0245. PMID 10534439.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Pubchem. "Gypenoside A". Retrieved 2018-07-14.

[1] Lu, Kung-Wen; Chen, Jung-Chou; Lai, Tung-Yuan; Yang, Jai-Sing; Weng, Shu-Wen; Ma, Yi-Shih; Tang, Nou-Ying; Lu, Pei-Jung; Weng, Jing-Ru; Chung, Jing-Gung (2010-05-01). "Gypenosides Causes DNA Damage and Inhibits Expression of DNA Repair Genes of Human Oral Cancer SAS Cells". In Vivo. 24 (3): 287–291. ISSN 0258-851X. PMID 20555000. Retrieved 2018-07-14.

[2] Tanner, MA; Bu, X; Steimle, JA; Myers, PR (1999). "The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum". Nitric Oxide. 3 (5): 359–365. doi:10.1006/niox.1999.0245. PMID 10534439.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[3] Pubchem. "Gypenoside A". Retrieved 2018-07-14.

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