Talk:Barbiturate overdose

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Mechanism of action and synergy

The article states "Benzodiazepines increase the frequency of chloride channel opening while barbiturates increase the duration that the chloride pore remains open."

I find it extremely hard to believe that these two agents differ in this sense, especially without a high quality reference. Binding of either drug increases GABA-mediated chloride conductance thourgh increasing total cloride ion influx. The frequency vs. duration approach seems to me to be an oversimplified way of explaining drug synergy, which does not serve it's purpuse and is very misleading. — Preceding unsigned comment added by 93.103.78.229 (talk) 17:19, 5 April 2015 (UTC)[reply]

Redundant treatment info

Why is the *entirety* of the treatment section copied into the header description? Should this just be removed? Teddy error (talk) 06:16, 10 April 2020 (UTC)[reply]