Elizabeth D. Getzoff
This article, Elizabeth D. Getzoff, has recently been created via the Articles for creation process. Please check to see if the reviewer has accidentally left this template after accepting the draft and take appropriate action as necessary.
Reviewer tools: Inform author |
This article, Elizabeth D. Getzoff, has recently been created via the Articles for creation process. Please check to see if the reviewer has accidentally left this template after accepting the draft and take appropriate action as necessary.
Reviewer tools: Inform author |
Elizabeth D. Getzoff is Professor Emeritus (Joint Appointment) in Immunology & Microbiology and Integrative Structural and Computational Biology (ISCB) at Scripps Research Institute in California..[1]
Education and career
Getzoff received her Chemistry degree at Duke University in 1976, where she also completed her doctoral studies in Biochemistry in 1982. In 1983 she became a Faculty Member of the Skaggs Institute for Chemical Biology[2] and Professor in Molecular Biology at Scripps Research. In 2012 was appointed Professor in Immunology and Microbial Science, in 2013 she was appointed Professor in Integrative Structural and Computational Biology and in 2017 she was appointed Professor in Immunology and Microbiology at Scripps Research.
Research interest
Getzoff is currently leading a research group at the Scripps Research Institute[3]. The main focus of her team is the characterisation of protein conformational changes in cellular pathways, such as protein recognition, interaction and catalysis. In particular, they are interested in proteins involved in photosensing, in the enzymatic control of reactive oxygen and nitrogen species, in the coupling of metal-site chemistry and electron transfer for catalysis, and in protein networks involved in circadian rhythms. In their studies, they use multidisciplinary approachesthat include high-resolution protein crystallography, computational and computer graphics analysis, protein design cycles, small angle X-ray scattering, biochemical and spectroscopic analyses, and further molecular biology techniques[4]
Publications
Her most cited publications are
- Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science. 1993 Aug 20;261(5124):1047-51. According to Google Scholar, it has been cited 1652 times.[5]
- Tainer JA, Getzoff ED, Richardson JS, Richardson DC. Structure and mechanism of copper, zinc superoxide dismutase. Nature. 1983 Nov;306(5940):284-7. According to Google Scholar, this article has been cited 1044 times [5]
- Tainer JA, Getzoff ED, Beem KM, Richardson JS, Richardson DC. Determination and analysis of the 2 Å structure of copper, zinc superoxide dismutase. Journal of molecular biology. 1982 Sep 15;160(2):181-217. According to Google Scholar, this article has been cited 1158 times [5]
- Crane BR, Arvai AS, Ghosh DK, Wu C, Getzoff ED, Stuehr DJ, Tainer JA. Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science. 1998 Mar 27;279(5359):2121-6. According to Google Scholar, this article has been cited 780 times [5]
References
- ^ "Getzoff, Elizabeth". vivo.scripps.edu. Retrieved 2020-03-07.
- ^ "Skaggs Institute for Chemical Biology | Scripps Research". www.scripps.edu. Retrieved 2020-03-07.
- ^ "ELIZABETH D. GETZOFF LABORATORY". www.scripps.edu. Retrieved 2020-03-07.
- ^ pubmeddev. "Elizabeth D. Getzoff - PubMed - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-03-07.
- ^ a b c d [1] Google Scholar Author page, Accessed August 17, 2020