Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Ageliferin: Difference between pages
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Saving copy of the {{chembox}} taken from revid 471353725 of page Ageliferin for the Chem/Drugbox validation project (updated: 'ChEMBL', 'CASNo'). |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid [{{fullurl:Ageliferin|oldid=471353725}} 471353725] of page [[Ageliferin]] with values updated to verified values.}} |
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|verifiedrevid = 477243588 |
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|ImageFile = Ageliferin.png |
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|ImageSize = 200px |
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|PIN = ''N'',''N''′-<nowiki/>{[(4''R'',5''R'',6''S'')-2-Amino-4-(2-amino-1''H''-imidazol-5-yl)-4,5,6,7-tetrahydro-1''H''-1,3-benzimidazole-5,6-diyl]bis(methylene)}bis(4-bromo-1''H''-pyrrole-2-carboxamide) |
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|OtherNames = Ageliferine |
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|Section1={{Chembox Identifiers |
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|ChEMBL = 502866 |
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| ChEMBL = <!-- blanked - oldvalue: 502866 --> |
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|SMILES = C1[C@@H]([C@H]([C@@H](C2=C1NC(=N2)N)C3=CN=C(N3)N)CNC(=O)C4=CC(=CN4)Br)CNC(=O)C5=CC(=CN5)Br |
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|InChI = 1/C22H24Br2N10O2/c23-10-2-14(27-5-10)19(35)29-4-9-1-13-18(34-22(26)32-13)17(16-8-31-21(25)33-16)12(9)7-30-20(36)15-3-11(24)6-28-15/h2-3,5-6,8-9,12,17,27-28H,1,4,7H2,(H,29,35)(H,30,36)(H3,25,31,33)(H3,26,32,34)/t9-,12-,17-/m1/s1 |
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| CASNo = <!-- blanked - oldvalue: 117417-64-8 --> |
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| SMILES = Brc1cc(nc1)C(=O)NC[C@H]3Cc5nc(N)nc5C([C@@H]3CNC(=O)c2cc(Br)cn2)c4cnc(N)n4 |
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|CASNo = 117417-64-8 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = P4YF5N7VXX |
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|Section2={{Chembox Properties |
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|C=22 | H=24 | Br=2 | N=10 | O=2 |
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| Section3 = {{Chembox Hazards |
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'''Ageliferin''' is a [[chemical compound]] produced by some [[sponge]]s. It was first isolated from Caribbean and then Okinawan marine sponges in the genus ''[[Agelas]]''.<ref>{{cite journal |author= Rinehart, Kenneth L |title= Bioactive Compounds from Aquatic and Terrestrial Sources |journal= Journal of Natural Products |year= 1990 |volume= 53 |issue= 4 |pages= 771–792 |doi= 10.1021/np50070a001|pmid= 2095373 |display-authors=etal}}</ref><ref>{{cite journal |author= Keifer, Paul A. |title= Bioactive Bromopyrrole Metabolites from the Caribbean Sponge Agelas conifera |journal= J. Org. Chem. |year= 1991 |volume= 56 |issue= 9 |pages= 2965–75 |doi= 10.1021/jo00009a008|display-authors=etal}}</ref><ref>{{cite journal |author= Kobayashi, Junichi |title= Ageliferins, potent actomyosin ATPase activators from the Okinawan marine sponge Agelas sp. |journal= Tetrahedron |year= 1990 |volume= 46 |issue= 16 |pages= 5579–86 |doi= 10.1016/S0040-4020(01)87756-5|display-authors=etal}}</ref> It often co-exists with the related compound [[sceptrin]] and other similar compounds. It has antibacterial properties and can cause [[biofilm]]s to dissolve.<ref>{{cite journal |title= Sponge's secret weapon restores antibiotics' power: Bacteria treated with compound lose their resistance |journal= Science News |author= Laura Sanders |year= 2009 |volume= 175 |issue= 6 |pages= 16 |url= http://www.sciencenews.org/view/generic/id/40894/title/Sponge%27s_secret_weapon_restores_antibiotics%27_power |doi=10.1002/scin.2009.5591750616}}</ref> |
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==See also== |
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* ''[[Agelas clathrodes]]'' |
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* ''[[Agelas conifera]]'' |
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== References == |
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{{reflist}} |
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{{Alkaloid-stub}} |
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[[Category:Halogen-containing alkaloids]] |
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[[Category:Organobromides]] |
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[[Category:Pyrroles]] |
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[[Category:Benzimidazoles]] |
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[[Category:Carboxamides]] |