Cephaeline: Difference between revisions

| verifiedrevid = 708748834

| IUPACName = (1''R'')-1-<nowiki>[[</nowiki>(2''S'',3''R'',11b''S'')-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1''H''-pyrido[2,1-''a'']isoquinolin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol

| PubChem = 442195

'''Cephaeline''' is an [[alkaloid]] that is found in ''[[Cephaelis ipecacuanha]]'' and other plant species including ''[[cephaelis|Psychotria acuminata]]''.<ref>{{cite news|url=http://www.accessmylibrary.com/article-1G1-119570434/micropropagaci195179n-de-la-planta.html|title=Micropropagacion de la planta medicinal psychotria acuminata|last=Lara, Alfonso; Valverde, Roberto; Gomez, Luis; Hidalgo, Nancy| date=July 1, 2003 |work=Agronomía Costarricense| accessdate=26 December 2009}}</ref> Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as [[syrup of ipecac]].<ref>{{cite news|url=http://www.accessmylibrary.com/article-1G1-72449957/pharma-japan-approval-4.html|title=Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel.|date=November 14, 2000 |work=Chemical Business Newsbase |accessdate=26 December 2009}}</ref> Chemically, it is closely related to [[emetine]].

Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.<ref>{{cite journal |journal=Pediatrics |volume=112 |issue=5 |date=November 2003 |pages=1182–1185 |title=Policy statement: Poison treatment in the home |url=http://aappolicy.aappublications.org/cgi/content/full/pediatrics;112/5/1182 |doi=10.1542/peds.112.5.1182 |pmid=14595067| accessdate=31 December 2009}}</ref>

[[Category:Alkaloids]]

[[Category:Phenol ethers]]

[[Category:Tetrahydroisoquinolines]]

[[Category:Pyridoisoquinolines]]