ICRF 193: Difference between revisions
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Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: ChEMBL. |
m Open access bot: doi added to citation with #oabot. |
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{{chembox |
{{chembox |
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| verifiedrevid = |
| verifiedrevid = 415659765 |
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|ImageFile=ICRF 193.png |
| ImageFile=ICRF 193.png |
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|ImageSize=200px |
| ImageSize=200px |
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|IUPACName=4-[2-(3,5-Dioxo-1-piperazinyl)-1-methylpropyl]piperazine-2,6-dione |
| IUPACName=4-[2-(3,5-Dioxo-1-piperazinyl)-1-methylpropyl]piperazine-2,6-dione |
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|OtherNames= |
| OtherNames= |
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|Section1={{Chembox Identifiers |
|Section1={{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 103034 |
| ChemSpiderID = 103034 |
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| InChI = 1/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(20)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20) |
| InChI = 1/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(20)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20) |
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| InChIKey = OBYGAPWKTPDTAS-UHFFFAOYAB |
| InChIKey = OBYGAPWKTPDTAS-UHFFFAOYAB |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 275665 |
| ChEMBL = 275665 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = OBYGAPWKTPDTAS-UHFFFAOYSA-N |
| StdInChIKey = OBYGAPWKTPDTAS-UHFFFAOYSA-N |
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| CASNo_Ref = {{cascite|correct|??}} |
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| CASNo=21416-68-2 |
| CASNo=21416-68-2 |
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| PubChem=115150 |
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| SMILES = O=C2NC(=O)CN(C(C(N1CC(=O)NC(=O)C1)C)C)C2 |
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| MeSHName=ICRF+193 |
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|Section2={{Chembox Properties |
|Section2={{Chembox Properties |
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| Formula=C<sub>12</sub>H<sub>18</sub>N<sub>4</sub>O<sub>4</sub> |
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| MolarMass=282.30 g/mol |
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| Appearance= |
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| Density= |
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| MeltingPt= |
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|Section3={{Chembox Hazards |
|Section3={{Chembox Hazards |
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| MainHazards= |
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| FlashPt= |
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| AutoignitionPt = |
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| Autoignition= |
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'''ICRF 193''' is a [[topoisomerase inhibitor]].<ref name="pmid17495539">{{cite journal | |
'''ICRF 193''' is a [[topoisomerase inhibitor]].<ref name="pmid17495539">{{cite journal |vauthors=Robinson HM, Bratlie-Thoresen S, Brown R, Gillespie DA |title=Chk1 is required for G2/M checkpoint response induced by the catalytic topoisomerase II inhibitor ICRF-193 |journal=Cell Cycle |volume=6 |issue=10 |pages=1265–7 |date=May 2007 |pmid=17495539 |doi= 10.4161/cc.6.10.4225|url=http://www.landesbioscience.com/journals/cc/abstract.php?id=4225|doi-access=free }}</ref> |
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==References== |
==References== |
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[[Category:Imides]] |
[[Category:Imides]] |
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[[Category: |
[[Category:Diketopiperazines]] |
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[[Category: |
[[Category:Topoisomerase inhibitors]] |
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{{organic-compound-stub}} |
{{organic-compound-stub}} |
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[[sr:ICRF 193]] |