Oxidized cellulose: Difference between revisions

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'''Oxidized cellulose''' is a water-insoluble derivative of [[cellulose]]. It can be produced from cellulose by the action of an oxidizing agent, such as [[chlorine]], [[hydrogen peroxide]], [[peracetic acid]], [[chlorine dioxide]], [[nitrogen dioxide]], [[persulfate]]s, [[permanganate]], dichromate-[[sulfuric acid]], [[hypochlorous acid]], [[hypohalite]]s or [[periodate]]s and a variety of metal [[Catalysis|catalysts]].<ref name=collinson-catox>{{cite journal| vauthors = Collinson SR, Thielemans W | title = The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin. | journal = Coordination Chemistry Reviews | date = August 2010 | volume = 254 | issue = 15–16 | pages = 1854–1870 | doi = 10.1016/j.ccr.2010.04.007 |url= http://oro.open.ac.uk/31289/19/Catalytic_oxidation_of_biomass_to_new_materials.pdf }}</ref> Oxidized cellulose may contain [[carboxylic acid]], [[aldehyde]], and/or [[ketone]] groups, in addition to the original [[Hydroxy group|hydroxyl groups]] of the starting material, [[cellulose]], depending on the nature of the oxidant and reaction conditions.<ref>{{Cite patent | country = US | number = 5780618 | url=https://patents.google.com/patent/US5780618A/en?oq=US5780618 | title=Oxidized cellulose | inventor = Banker GS, Kumar V | assign = Biocontrol Inc.| gdate = 14 July 1998 }}</ref>

It is an [[antihemorrhagic]].<ref name="pmid10350276">{{cite journal | vauthors = Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS | title = MR characteristics of oxidized cellulose (Surgicel) | journal = AJR. American Journal of Roentgenology | volume = 172 | issue = 6 | pages = 1481–1484 | date = June 1999 | pmid = 10350276 | doi = 10.2214/ajr.172.6.10350276 | doi-access = free }}</ref> It works both by absorbing the blood (similar to a cotton ball)<ref>{{cite web |title=Oxidised Cellulose |url=https://www.admedsol.com/our-technologies/oxidised-cellulose |website=Advanced Medical Solutions Group plc|date=30 November 2023 }}</ref> and by triggering the [[contact activation system]]. It is poorly absorbed and may cause healing complications postoperatively.<ref>{{cite book | vauthors = Resnik RR |chapter= Intraoperative Complications | veditors = Resnik RR, Misch CE |title=Misch's Avoiding Complications in Oral Implantology |date=2018 |pages=267–293 |doi=10.1016/B978-0-323-37580-1.00007-X|isbn=978-0-323-37580-1 }}</ref>

== See also ==

* [[Regenerated cellulose]]

== References ==