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PSN-632,408: Difference between revisions

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Updating {{drugbox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (
 
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{{Short description|Chemical compound}}
{{Drugbox
{{Drugbox
| verifiedrevid = 386416659
| verifiedrevid = 424766281
| IUPAC_name = ''tert''-butyl 4-[(3-pyridin-4-yl-1,2,4-oxadiazol-5-yl)methoxy]piperidine-1-carboxylate
| IUPAC_name = ''tert''-butyl 4-[(3-pyridin-4-yl-1,2,4-oxadiazol-5-yl)methoxy]piperidine-1-carboxylate
| image = PSN-632408-structure.png
| image = PSN-632408-structure.png

| CAS_number = 857652-30-3
<!--Clinical data-->
| ATC_prefix = none
| tradename =
| ATC_suffix =
| pregnancy_category =
| PubChem = 11462546
| legal_status =
| C = 18 | H = 24 | N = 4 | O = 4
| routes_of_administration =
| molecular_weight = 360.407 g/mol

| smiles = CC(C)(C)OC(=O)N1CCC(CC1)OCc2nc(no2)-c3ccncc3
<!--Pharmacokinetic data-->
| bioavailability =
| bioavailability =
| metabolism =
| metabolism =
| elimination_half-life =
| elimination_half-life =
| excretion =
| excretion =
| pregnancy_category =

| legal_status =
<!--Identifiers-->
| routes_of_administration =
| IUPHAR_ligand = 3319
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 857652-30-3
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = V4434XWK2P
| ATC_prefix = none
| PubChem = 11462546
| ChemSpiderID = 9637386
| ChEMBL = 1081913

<!--Chemical data-->
| C=18 | H=24 | N=4 | O=4
| smiles = CC(C)(C)OC(=O)N1CCC(CC1)OCc2nc(no2)-c3ccncc3
| StdInChI = 1S/C18H24N4O4/c1-18(2,3)25-17(23)22-10-6-14(7-11-22)24-12-15-20-16(21-26-15)13-4-8-19-9-5-13/h4-5,8-9,14H,6-7,10-12H2,1-3H3
| StdInChIKey = LHZWKWCEAXQUMX-UHFFFAOYSA-N
}}
}}


'''PSN-632,408''' is a [[binding_selectivity|selective]] [[ligand]] for the suggested novel [[cannabinoid receptor]] [[GPR119]].<ref name="pmid16517404">{{cite journal |author = Overton HA, Babbs AJ, Doel SM, Fyfe MC, Gardner LS, Griffin G, Jackson HC, Procter MJ, Rasamison CM, Tang-Christensen M, Widdowson PS, Williams GM, Reynet C. |title = Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. | journal = Cell Metab. | volume = 3 | issue = 3 | pages = 167–175 | year = 2006 |pmid = 16517404 |doi = 10.1016/j.cmet.2006.02.004 }}</ref>
'''PSN-632,408''' is a [[binding selectivity|selective]] [[ligand]] for the suggested novel [[cannabinoid receptor]] [[GPR119]].<ref name="pmid16517404">{{cite journal |vauthors = Overton HA, Babbs AJ, Doel SM, Fyfe MC, Gardner LS, Griffin G, Jackson HC, Procter MJ, Rasamison CM, Tang-Christensen M, Widdowson PS, Williams GM, Reynet C |title = Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. | journal = Cell Metab. | volume = 3 | issue = 3 | pages = 167–175 | year = 2006 |pmid = 16517404 |doi = 10.1016/j.cmet.2006.02.004 | doi-access = free }}</ref>


== See also ==
== See also ==
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== References ==
== References ==
{{Reflist|2}}
{{Reflist}}



{{Cannabinoids}}
{{Cannabinoids}}


[[Category:4-Pyridyl compounds]]

{{cannabinoid-stub}}

[[Category:Pyridines]]
[[Category:Oxadiazoles]]
[[Category:Oxadiazoles]]
[[Category:Piperidines]]
[[Category:Piperidines]]
[[Category:Carbamates]]
[[Category:Carbamates]]
[[Category:Tert-butyl compounds]]


{{cannabinoid-stub}}