Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Phenicarbazide: Difference between pages
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Saving copy of the {{drugbox}} taken from revid 456775137 of page Phenicarbazide for the Chem/Drugbox validation project (updated: 'KEGG', 'CAS_number'). |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid [{{fullurl:Phenicarbazide|oldid=456775137}} 456775137] of page [[Phenicarbazide]] with values updated to verified values.}} |
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{{Drugbox |
{{Drugbox |
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| Verifiedfields = changed |
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| IUPAC_name = 2-Phenylhydrazinecarboxamide |
| IUPAC_name = 2-Phenylhydrazinecarboxamide |
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| image = Phenicarbazide structure.svg |
| image = Phenicarbazide structure.svg |
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<!--Identifiers--> |
<!--Identifiers--> |
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| CAS_number_Ref = {{cascite| |
| CAS_number_Ref = {{cascite|changed|??}} |
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| CAS_number = |
| CAS_number = 103-03-7 |
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| CAS_supplemental = |
| CAS_supplemental = |
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| ATC_prefix = none |
| ATC_prefix = none |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 54963 |
| ChemSpiderID = 54963 |
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| UNII_Ref = {{fdacite| |
| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 1LR2578324 |
| UNII = 1LR2578324 |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
| KEGG_Ref = {{keggcite|changed|kegg}} |
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| KEGG = |
| KEGG = C19498 |
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<!--Chemical data--> |
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| chemical_formula = |
| chemical_formula = |
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| C=7 | H=9 | N=3 | O=1 |
| C=7 | H=9 | N=3 | O=1 |
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| molecular_weight = 151.166 g/mol |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C7H9N3O/c8-7(11)10-9-6-4-2-1-3-5-6/h1-5,9H,(H3,8,10,11) |
| StdInChI = 1S/C7H9N3O/c8-7(11)10-9-6-4-2-1-3-5-6/h1-5,9H,(H3,8,10,11) |
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| StdInChIKey_Ref = {{stdinchicite| |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = AVKHCKXGKPAGEI-UHFFFAOYSA-N |
| StdInChIKey = AVKHCKXGKPAGEI-UHFFFAOYSA-N |
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| synonyms = 1-Phenylsemicarbazide; Kryogenin |
| synonyms = 1-Phenylsemicarbazide; Kryogenin |
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}} |
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'''Phenicarbazide''' is a [[semicarbazide]] and an [[antipyretic]] substance. It is carcinogenic in mice.<ref name="phenicarbazide">{{cite web | url = http://www.inchem.org/documents/iarc/vol12/phenicarbazide.html | title = Phenicarbazide | work = International Agency for Research on Cancer (IARC) - Summaries & Evaluations | date = 25 March 1998 }}</ref> |
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== Preparation == |
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Phenicarbazide can be obtained by mixing [[phenylhydrazine]] with [[acetic acid]] in aqueous solution with the addition of [[potassium cyanide]]. It is also obtained from the reaction of phenylhydrazine with [[urea]].<ref>{{Cite book | vauthors = Bruchhausen F, Ebel S, Hackenthal E, Holzgrabe U, Albinus M, Amschler G, Angerer E |url=https://www.worldcat.org/oclc/913646782 |title=Hagers Handbuch der Pharmazeutischen Praxis : Stoffe L-Z Folgeband 5 |date=1999 |isbn=978-3-642-58388-9 |edition=5. vollständig neubearbeitete Auflage |location=Berlin, Heidelberg |pages=420 |oclc=913646782}}</ref> |
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== Properties == |
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Phenicarbazide is a flammable, hard to ignite, crystalline, beige solid that is practically insoluble in water. It decomposes on heating.<ref>{{Cite web |title=Phenicarbazid |url=https://gestis.dguv.de/data?name=031670 |access-date=2022-10-18 |website=GESTIS-Stoffdatenbank}}</ref> |
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== Uses == |
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Phenicarbazide is an intermediate in the syntheses of a series of chemical compounds by cyclocondensation reactions.<ref>{{Cite web |title=1-Phenylsemicarbazide |url=https://www.sigmaaldrich.com/US/en/product/aldrich/245909 |website=Sigma-Aldrich}}</ref> It was investigated as an [[analgesic]] and [[antipyretic]] in the 1970s and was used in combination preparations. |
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== References == |
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{{Reflist}} |
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[[Category:Semicarbazides]] |
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[[Category:Anilines]] |
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{{Analgesic-stub}} |
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