Jump to content

Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Rokitamycin: Difference between pages

(Difference between pages)
Page 1
Page 2
Content deleted Content added
VisualWikitext
Saving copy of the {{drugbox}} taken from revid 456696952 of page Rokitamycin for the Chem/Drugbox validation project (updated: 'ChEMBL', 'CAS_number').
 
Add: s2cid. | Use this bot. Report bugs. | #UCB_CommandLine 301/644
 
Line 1: Line 1:
{{Short description|Type of antibiotic chemical}}
{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid [{{fullurl:Rokitamycin|oldid=456696952}} 456696952] of page [[Rokitamycin]] with values updated to verified values.}}
{{Drugbox
{{Drugbox
| Verifiedfields = changed
| Verifiedfields = changed
⚫
| verifiedrevid = 464383231
| Watchedfields = changed
⚫
| IUPAC_name = (2''S'',3''S'',4''R'',6''S'')-6-<nowiki/>{[(2''R'',3''S'',4''R'',5''R'',6''S'')-6-<nowiki/>{[(4''R'',5''S'',6''S'',7''R'',9''R'',10''R'',11''E'',13''E'',16''R'')-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-4-propoxyoxan-3-yl butanoate
⚫
| verifiedrevid = 401043816
⚫
| IUPAC_name = (2''S'',3''S'',4''R'',6''S'')-6-{[(2''R'',3''S'',4''R'',5''R'',6''S'')-6-{[(4''R'',5''S'',6''S'',7''R'',9''R'',10''R'',11''E'',13''E'',16''R'')-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-4-propoxyoxan-3-yl butanoate
| image = rokitamycin.png
| image = rokitamycin.png


<!--Clinical data-->
<!--Clinical data-->
| tradename =
| tradename =
| Drugs.com = {{drugs.com|international|rokitamycin}}
| Drugs.com = {{drugs.com|international|rokitamycin}}
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
Line 18: Line 17:


<!--Identifiers-->
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = <!-- blanked - oldvalue: 74014-51-0 -->
| CAS_number = 74014-51-0
| ATC_prefix = J01
| ATC_prefix = J01
| ATC_suffix = FA12
| ATC_suffix = FA12
Line 26: Line 25:
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4445397
| ChemSpiderID = 4445397
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ZPT03UEM0E
| UNII = ZPT03UEM0E
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = <!-- blanked - oldvalue: 556528 -->
| ChEMBL = 1908350

⚫
| C=42 | H=71 | N=1 | O=14
<!--Chemical data-->
| molecular_weight = 827.999 g/mol
⚫
| C=42 | H=71 | N=1 | O=14
| smiles = O=CC[C@H]3C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@H](OC(=O)C[C@@H](O)[C@H](OC)[C@H]3O[C@@H]2O[C@@H]([C@@H](O[C@@H]1O[C@H]([C@H](OC(=O)CCC)[C@](OC(=O)CC)(C1)C)C)[C@H](N(C)C)[C@H]2O)C)C
| smiles = O=CC[C@H]3C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@H](OC(=O)C[C@@H](O)[C@H](OC)[C@H]3O[C@@H]2O[C@@H]([C@@H](O[C@@H]1O[C@H]([C@H](OC(=O)CCC)[C@](OC(=O)CC)(C1)C)C)[C@H](N(C)C)[C@H]2O)C)C
| InChI = 1/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
| InChIKey = VYWWNRMSAPEJLS-MDWYKHENBZ
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
| StdInChI = 1S/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
Line 40: Line 38:
| StdInChIKey = VYWWNRMSAPEJLS-MDWYKHENSA-N
| StdInChIKey = VYWWNRMSAPEJLS-MDWYKHENSA-N
| melting_point = 116
| melting_point = 116
| solubility = Insoluble in water; Very soluble in [[chloroform]] and [[methanol]]; Almost completely (>99.5 %) in [[ethanol]] and [[acetonitrile]].
| solubility = Insoluble in water; Very soluble in [[chloroform]] and [[methanol]]; Almost completely (>99.5%) in [[ethanol]] and [[acetonitrile]].
}}
}}

'''Rokitamycin''' is a [[macrolide]] antibiotic synthesized from strains of ''Streptomyces kitasatoensis''.<ref name="pmid12017366">{{cite journal | vauthors = Braga PC | title = Rokitamycin: bacterial resistance to a 16-membered ring macrolide differs from that to 14- and 15-membered ring macrolides | journal = Journal of Chemotherapy | location = Florence, Italy | volume = 14 | issue = 2 | pages = 115–31 | date = April 2002 | pmid = 12017366 | doi = 10.1179/joc.2002.14.2.115 | s2cid = 1250525 }}</ref>

==References==
{{Reflist}}

==External links==
* [https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=Rokitamycin Recent Publications on Rokitamycin]

{{Macrolides, lincosamides and streptogramins}}

[[Category:Macrolide antibiotics]]


{{antibiotic-stub}}
Retrieved from "https://en.wikipedia.org/wiki/Special:ComparePages"