Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Satratoxin-H: Difference between pages

{{MCN|date=April 2024}}

| Verifiedfields = changed

| verifiedrevid = 464387474

|Section1={{Chembox Identifiers

| InChI = 1/C29H36O9/c1-17-7-10-27-15-34-24(32)13-19-8-11-35-28(18(2)30,25(19)33)9-5-4-6-23(31)38-20-14-22(37-21(27)12-17)29(16-36-29)26(20,27)3/h4-6,9,12-13,18,20-22,25,30,33H,7-8,10-11,14-16H2,1-3H3/b6-4-,9-5+,19-13+/t18-,20+,21+,22+,25+,26+,27+,28+,29+/m0/s1

| CASNo_Ref = {{cascite|changed|??}}

| CASNo=53126-64-0

| PubChem=6438478

| SMILES = C[C@H](O)[C@@]12\C=C\C=C/C(=O)O[C@@H]4C[C@H]6O[C@@H]3/C=C(/C)CC[C@]3(COC(=O)/C=C(\CCO1)[C@H]2O)[C@]4(C)[C@]56CO5

|Section2={{Chembox Properties

| Solubility=insoluble}}

|Section3={{Chembox Hazards

| GHSPictograms = {{GHS skull and crossbones}}

| MainHazards = Highly toxic}}

'''Satratoxin-H''', a [[trichothecene]] [[mycotoxin]], is a naturally occurring toxin produced by the [[ascomycetes]] ''[[Stachybotrys chartarum]]'' and ''[[Podostroma cornu-damae]]'' which is highly toxic to humans and animals. The clinical condition it causes is known as ''Stachybotrotoxicosis''. It is related to the mycotoxin [[T-2 mycotoxin|T-2]], but unlike T-2 has not been reported to have been used as a [[chemical weapon]].

== Properties ==

Satratoxin-H is almost completely insoluble in water, but is easily soluble in lower alcohols and polar solvents such as [[ethanol]], [[methanol]], [[2-propanol]], [[acetone]] and [[chloroform]].<ref>[http://www.cbwinfo.com/Biological/Toxins/Satra.html Satratoxin H:essential data] {{webarchive|url=https://web.archive.org/web/20070505162235/http://www.cbwinfo.com/Biological/Toxins/Satra.html |date=2007-05-05 }}</ref>

Satratoxin-H is not officially classified as a [[chemical weapon]]. {{citation needed|date=April 2017}}

== Effects ==

Satratoxin-H is extremely versatile. Contact with the solution through ingestion, inhalation, or even prolonged physical contact produces symptoms similar to those listed below.

* a rash that becomes a moist dermatitis

* [[nosebleed]]s

* chest pain

* [[pulmonary hemorrhage]] (bleeding in the lungs)

* fever

* headache

* fatigue

However, if consumed in large quantities, it can be lethal. Satratoxin-H has little effect on bare skin, and does not blister it in the way many chemical weapons do. However, upon contact with sensitive surfaces (eyes, interior of mouth or nose), inflammation will occur.

Satratoxin-H has an {{LD50}} for mice of 1.0-1.4&nbsp;mg/kg, upon injection. Otherwise it is reported to be about five times as toxic as T-2.<ref>[http://mason.gmu.edu/~pdonovan/Chem_350/Toxin.html#5Satratoxin-H, A mycotoxin with punch!]</ref>

== References ==

{{reflist}}

* {{ cite journal |author1=Croft, W. A. |author2=Jarvis, B. B. |author3=Yatawara, C. S. | title = Airborne outbreak of trichothecene toxicosis | journal = Atmospheric Environment | year = 1986 | volume = 20 | issue = 3 | pages = 549–552 | doi = 10.1016/0004-6981(86)90096-X |bibcode=1986AtmEn..20..549C }}

* {{ cite journal |author1=Nikulin, M. |author2=Reijula, K. |author3=Jarvis, B. B. |author4=Veijalainen, P. |author5=Hintikka, E. L. | title = Effects of Intranasal Exposure to Spores of ''Stachybotrys atra'' in Mice | journal = Fundamental and Applied Toxicology | year = 1997 | volume = 35 | issue = 2 | pages = 182–188 | pmid = 9038239 | doi=10.1093/toxsci/35.2.182| doi-access = free }}

[[Category:Trichothecenes]]

[[Category:Epoxides]]

[[Category:Protein synthesis inhibitors]]