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  • Cholinesterase reactivators are drugs that reverse the inhibition of cholinesterase by organophosphates or sulfonates. They are used as antidote for treating...
    975 bytes (80 words) - 16:09, 19 October 2024
  • defenses, leading to possible degradation of viral gene via cellular enzymes. Reactivation may be due to stress, UV light, etc. A provirus is a virus genome...
    18 KB (2,091 words) - 21:56, 6 October 2024
  • Thumbnail for MSPI (nerve agent)
    the acetylcholinesterase to form an aged enzyme adduct that can't be reactivated by cholinesterase reactivators. EA-2192 Guanitoxin Chabrier, P. E.; Jacob...
    1 KB (81 words) - 18:58, 15 September 2024
  • Thumbnail for Alkaline phosphatase
    The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme...
    55 KB (6,147 words) - 11:12, 12 September 2024
  • Thumbnail for Suicide inhibition
    mechanism-based inhibition, is an irreversible form of enzyme inhibition that occurs when an enzyme binds a substrate analog and forms an irreversible complex...
    5 KB (588 words) - 20:27, 18 September 2024
  • Thumbnail for Methionine synthase
    Methionine synthase (category Zinc enzymes)
    a self-reactivation mechanism, a reductive methylation process that uses S-adenosylmethionine as a distinct methyl donor. In humans, the enzyme is reduced...
    30 KB (3,437 words) - 07:25, 16 May 2024
  • Thumbnail for Pralidoxime
    Pralidoxime (category Cholinesterase reactivators)
    component (the esteric site) of the active site of the acetylcholinesterase enzyme, thereby blocking its activity. Pralidoxime binds to the other half (the...
    7 KB (678 words) - 08:59, 31 August 2024
  • Thumbnail for Photolyase
    Photolyase (category Enzymes of known structure)
    Photolyases (EC 4.1.99.3) are DNA repair enzymes that repair damage caused by exposure to ultraviolet light. These enzymes require visible light (from the violet/blue...
    15 KB (1,759 words) - 05:16, 23 September 2024
  • Thumbnail for Pyruvate dehydrogenase complex
    Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation...
    29 KB (3,340 words) - 20:01, 15 August 2024
  • Thumbnail for Acetylcholinesterase
    or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters...
    35 KB (3,880 words) - 16:55, 22 July 2024
  • chloride reactivates the poisoned enzyme (acetylcholinesterase) by scavenging the phosphoryl group attached on the functional hydroxyl group of the enzyme, counteracting...
    56 KB (6,500 words) - 08:10, 8 September 2024
  • Thumbnail for Disulfiram
    sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase, causing many of the effects of a hangover to be...
    32 KB (3,294 words) - 16:16, 23 September 2024
  • Thumbnail for FeMoco
    FeMoco (category Molybdenum enzymes)
    (FeMo cofactor) is the primary cofactor of nitrogenase. Nitrogenase is the enzyme that catalyzes the conversion of atmospheric nitrogen molecules N2 into...
    13 KB (1,568 words) - 06:52, 23 July 2024
  • Thumbnail for Sucrose-phosphate synthase
    Sucrose-phosphate synthase (category Enzymes of unknown structure)
    Sucrose-phosphate synthase (SPS) is a plant enzyme involved in sucrose biosynthesis. Specifically, this enzyme catalyzes the transfer of a hexosyl group...
    12 KB (1,330 words) - 18:42, 23 January 2024
  • Thumbnail for Glutathione peroxidase 4
    Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. GPX4 is a phospholipid hydroperoxidase that protects...
    19 KB (2,381 words) - 12:45, 8 October 2024
  • Thumbnail for Prokaryotic DNA replication
    gaps (or nicks) are filled with deoxyribonucleotides and sealed by the enzyme ligase. The rate of DNA replication in a living cell was first measured...
    17 KB (2,150 words) - 13:43, 23 June 2023
  • Thumbnail for Glutathione reductase
    reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase (EC 1.8...
    31 KB (3,709 words) - 04:25, 21 December 2023
  • Thumbnail for Soman
    described as "aging". Once the enzyme–OP complex has aged it is no longer regenerated by the common, oxime reactivators. The rate of this process is dependent...
    19 KB (2,115 words) - 14:26, 8 October 2024
  • Obidoxime (category Cholinesterase reactivators)
    the binding of organophosphorus compounds to the enzyme acetylcholinesterase (AChE). AChE is an enzyme that removes acetylcholine from the synapse after...
    5 KB (377 words) - 18:39, 22 September 2024
  • expression, which are theorized to be responsible for her condition. FAAH is an enzyme involved in the metabolism of endocannabinoids like anandamide. Cameron...
    25 KB (2,462 words) - 07:37, 15 October 2024
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