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  • Thumbnail for Platelet
    platelets do express tissue factor protein and carry both tissue factor pre-mRNA and mature mRNA. Platelet aggregation begins minutes after activation,...
    71 KB (8,533 words) - 15:40, 8 October 2024
  • Thumbnail for Prion
    Prion (redirect from Cellular prion protein)
    Soto C (June 2001). "Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding". Nature. 411 (6839): 810–813. Bibcode:2001Natur...
    99 KB (10,732 words) - 04:10, 18 October 2024
  • Thumbnail for Tau protein
    "prion-like" protein. Much like true prions, pathological tau aggregates have been shown to have the capacity to induce misfolding of native tau protein. Both...
    55 KB (6,241 words) - 00:08, 3 October 2024
  • Thumbnail for Amyloid
    Amyloid (redirect from Amyloid protein)
    amyloid protein structure is a different conformation from the one that the antibody recognizes. JUNQ and IPOD Proteopathy Protein aggregation predictors...
    60 KB (6,536 words) - 06:48, 29 August 2024
  • Thumbnail for TAR DNA-binding protein 43
    "Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation". Nature Communications. 8 (1): 45. Bibcode:2017NatCo...
    41 KB (4,646 words) - 22:19, 12 October 2024
  • Thumbnail for Coagulation
    repair. The process of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation...
    64 KB (6,553 words) - 13:35, 26 September 2024
  • Thumbnail for Tauopathy
    neurodegenerative diseases characterized by the aggregation of abnormal tau protein. Hyperphosphorylation of tau proteins causes them to dissociate from microtubules...
    18 KB (2,005 words) - 02:00, 18 October 2024
  • Thumbnail for Folding@home
    Folding@home (category Protein folds)
    provide a more complete picture of protein folding, misfolding, and aggregation. Due to the complexity of proteins' conformation or configuration space...
    154 KB (14,601 words) - 06:41, 27 July 2024
  • Thumbnail for Alpha-synuclein
    capable of briefly interacting with Syn and controlling its aggregation. The clinical and pathological findings support the hypothesis that aSyn disease in PD...
    83 KB (9,387 words) - 23:27, 26 September 2024
  • Thumbnail for Beta sheet
    form β-sheet-rich oligomeric structures associated with pathological states. The amyloid β protein's oligomeric form is implicated as a cause of Alzheimer's...
    27 KB (3,120 words) - 01:54, 14 August 2024
  • Thumbnail for Proteinopathy
    tauopathy, synucleinopathy, and the aggregation of superoxide dismutase-1 (SOD1), polyglutamine, and TAR DNA-binding protein-43 (TDP-43). In all of these instances...
    62 KB (4,598 words) - 21:08, 10 September 2024
  • Thumbnail for Major prion protein
    Soto C (June 2004). "Molecular mechanisms of neurotoxicity of pathological prion protein". Current Molecular Medicine. 4 (4): 397–403. doi:10.2174/1566524043360654...
    45 KB (5,140 words) - 15:04, 28 September 2024
  • in vivo amyloid imaging, which helps detect and quantify pathological protein aggregations in the brain of Alzheimer's patients. "MetLife Foundation...
    4 KB (148 words) - 02:02, 2 February 2023
  • Thumbnail for Neurodegenerative disease
    pathway that leads to the pathological accumulation of proteins in the brain. When the gene that encodes for amyloid precursor protein (APP) is spliced by...
    63 KB (6,939 words) - 08:36, 1 October 2024
  • Thumbnail for Lewy body
    Lewy bodies are the inclusion bodies – abnormal aggregations of protein – that develop inside neurons affected by Parkinson's disease (PD), the Lewy body...
    15 KB (1,687 words) - 22:41, 1 October 2024
  • Polytechnique Fédérale de Lausanne). His research focuses on protein misfolding and aggregation in the pathogenesis of Alzheimer's and Parkinson's diseases...
    17 KB (1,665 words) - 15:51, 8 August 2024
  • Thumbnail for Pathophysiology of Parkinson's disease
    major mechanisms for neuronal death in Parkinson's Disease include protein aggregation in Lewy bodies, disruption of autophagy, changes in cell metabolism...
    19 KB (2,216 words) - 15:41, 28 March 2024
  • Thumbnail for Serum amyloid P component
    component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its...
    6 KB (744 words) - 11:38, 20 October 2023
  • identify and observe tau protein aggregation both intra and intercellullary as well as their interaction with other proteins. Immunohistochemistry of...
    18 KB (2,128 words) - 05:35, 27 May 2024
  • Thumbnail for Hsp90
    Hsp90 (redirect from Heat shock protein 90)
    shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...
    51 KB (5,551 words) - 15:05, 1 October 2024
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