Clastogenic

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Clastogenic (/[invalid input: 'icon']klæstəˈɛn[invalid input: 'ɨ']k/)[1] is an adjective that describes the ability of an agent or process to act as a clastogen—an agent or process giving rise to or inducing disruption or breakages of chromosomes.

Biology

Clastogenic in biology is a term which refers to an agent or process giving rise to or inducing disruption or breakages, as of chromosomes.

Illustrative sentence: "This leads to the conclusion that a chemical that fails to induce a significant response in an in vitro clastogenicity assay is unlikely to be clastogenic in vivo, in bone marrow assays."[2]

Clastogens are mutagens which cause chromosome effects including breaks, rearrangements and changes in number.

Geology

Clastogenic in volcanic eruptions is a term which refers to an agent or process giving rise to or inducing disruption of the type of ejecta.

Illustrative sentence: "The complex features of this eruption can be explained by rapid deposition of coarse pyroclasts near the vent and the subsequent flowage of clastogenic lavas which were accompanied by a high eruption plume generating pumice falls and/or pyroclastic flows."[3]

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