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'''Nevus of Ota''' (also known as "congenital melanosis bulbi,"<ref name="Bolognia">{{cite book |author=Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages=1720–22 |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref> "nevus fuscoceruleus ophthalmomaxillaris," "oculodermal melanocytosis",<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|700}} and "Oculomucodermal melanocytosis"<ref name="Bolognia" />) is a blue hyperpigmentation<ref name="pmid14673306">{{cite journal |author=Chan HH, Kono T |title=Nevus of Ota: clinical aspects and management |journal=Skinmed |volume=2 |issue=2 |pages=89–96; quiz 97–8 |year=2003 |pmid=14673306 |doi= 10.1111/j.1540-9740.2003.01706.x|url=http://www.lejacq.com/articleDetail.cfm?pid=SKINmed_2;2:89}}</ref> that occurs on the face. It was first reported by Dr. [[Mokutaro Kinoshita|M. T. Ota]] of Japan in 1939.<ref name="titleeMedicine - Nevi of Ota and Ito : Article by Harvey Lui">{{cite web |url=http://www.emedicine.com/DERM/topic290.htm |title=eMedicine - Nevi of Ota and Ito : Article by Harvey Lui |accessdate=2008-03-22 |work=}}</ref>
'''Nevus of Ota''' (also known as "congenital melanosis bulbi,"<ref name="Bolognia">{{cite book |author=Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages=1720–22 |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref> "naevus fuscocaeruleus ophthalmomaxillaris," "oculodermal melanocytosis",<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|700}} and "Oculomucodermal melanocytosis"<ref name="Bolognia" />) is a blue hyperpigmentation<ref name="pmid14673306">{{cite journal |author=Chan HH, Kono T |title=Nevus of Ota: clinical aspects and management |journal=Skinmed |volume=2 |issue=2 |pages=89–96; quiz 97–8 |year=2003 |pmid=14673306 |doi= 10.1111/j.1540-9740.2003.01706.x|url=http://www.lejacq.com/articleDetail.cfm?pid=SKINmed_2;2:89}}</ref> that occurs on the face. It was first reported by Dr. [[Mokutaro Kinoshita|M. T. Ota]] of Japan in 1939.<ref name="titleeMedicine - Nevi of Ota and Ito : Article by Harvey Lui">{{cite web |url=http://www.emedicine.com/DERM/topic290.htm |title=eMedicine - Nevi of Ota and Ito : Article by Harvey Lui |accessdate=2008-03-22 |work=}}</ref>


Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of [[glaucoma]]). It should not be confused with [[Mongolian spot]], which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be [[congenital]], and may appear during [[puberty]].
Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of [[glaucoma]]). It should not be confused with [[Mongolian spot]], which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be [[congenital]], and may appear during [[puberty]].

Revision as of 15:23, 4 June 2013

Nevus of Ota
SpecialtyOncology Edit this on Wikidata

Nevus of Ota (also known as "congenital melanosis bulbi,"[1] "naevus fuscocaeruleus ophthalmomaxillaris," "oculodermal melanocytosis",[2]: 700  and "Oculomucodermal melanocytosis"[1]) is a blue hyperpigmentation[3] that occurs on the face. It was first reported by Dr. M. T. Ota of Japan in 1939.[4]

Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of glaucoma). It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be congenital, and may appear during puberty.

Treatment

Q-switched laser has been used for treatment.[5][6]

Hydroquinone preparations are also helpful in partially treating this defect.

Notable people

Actress Daniela Ruah

See also

References

  1. ^ a b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1720–22. ISBN 1-4160-2999-0.{{cite book}}: CS1 maint: multiple names: authors list (link)
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. {{cite book}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  3. ^ Chan HH, Kono T (2003). "Nevus of Ota: clinical aspects and management". Skinmed. 2 (2): 89–96, quiz 97–8. doi:10.1111/j.1540-9740.2003.01706.x. PMID 14673306.
  4. ^ "eMedicine - Nevi of Ota and Ito : Article by Harvey Lui". Retrieved 2008-03-22.
  5. ^ Geronemus R. "Q-switched ruby laser therapy of nevus of Ota". Arch Dermatol. 128:1618-1622. 1992 [1]
  6. ^ Watanabe S, Takahashi H (1994). "Treatment of nevus of Ota with the Q-switched ruby laser". N. Engl. J. Med. 331 (26): 1745–50. doi:10.1056/NEJM199412293312604. PMID 7984195.