Etilevodopa: Difference between revisions
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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Drugbox |
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| verifiedrevid = |
| verifiedrevid = 443949574 |
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| IUPAC_name |
| IUPAC_name = ethyl (2''S'')-2-amino-3-(3,4-dihydroxyphenyl)propanoate |
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| image |
| image = Etilevodopa.svg |
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| width = 240 |
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| image2 = Etilevodopa 3D ball.png |
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| alt2 = Ball-and-stick model of the etilevodopa molecule |
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<!--Clinical data--> |
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| tradename = |
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<!--Pharmacokinetic data--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| ATC_supplemental = (combination with [[decarboxylase inhibitor]]) |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 148944 |
| ChemSpiderID = 148944 |
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| InChI = 1/C11H15NO4/c1-2-16-11(15)8(12)5-7-3-4-9(13)10(14)6-7/h3-4,6,8,13-14H,2,5,12H2,1H3/t8-/m0/s1 |
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| InChIKey = NULMGOSOSZBEQL-QMMMGPOBBX |
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<!--Chemical data--> |
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| smiles = O=C(OCC)[C@@H](N)Cc1cc(O)c(O)cc1 |
| smiles = O=C(OCC)[C@@H](N)Cc1cc(O)c(O)cc1 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = NULMGOSOSZBEQL-QMMMGPOBSA-N |
| StdInChIKey = NULMGOSOSZBEQL-QMMMGPOBSA-N |
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| molecular_weight = 225.241 g/mol |
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'''Etilevodopa''' ('''TV-1203''') is a [[dopaminergic]] agent which was developed as a treatment for [[Parkinson's disease]].<ref>{{cite journal | vauthors = Djaldetti R, Giladi N, Hassin-Baer S, Shabtai H, Melamed E | title = Pharmacokinetics of etilevodopa compared to levodopa in patients with Parkinson's disease: an open-label, randomized, crossover study | journal = Clinical Neuropharmacology | volume = 26 | issue = 6 | pages = 322–6 | date = November–December 2003 | pmid = 14646613 | doi = 10.1097/00002826-200311000-00012 | s2cid = 23992241 }}</ref> It is the [[ethyl group|ethyl]] [[ester]] of [[levodopa]]. It was never marketed. |
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'''Etilevodopa''' is a [[dopaminergic]] agent. It is the [[ethyl group|ethyl]] [[ester]] of [[levodopa]]. |
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== See also == |
== See also == |
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== References == |
== References == |
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{{Reflist |
{{Reflist}} |
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{{Antiparkinsonian}} |
{{Antiparkinsonian}} |
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{{Phenethylamines}} |
{{Phenethylamines}} |
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[[Category:Neurotransmitter precursors]] |
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[[Category:Catecholamines]] |
[[Category:Catecholamines]] |
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[[Category:Dopamine agonists]] |
[[Category:Dopamine agonists]] |
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[[Category: |
[[Category:Propionate esters]] |
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[[Category:Abandoned drugs]] |
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{{nervous-system-drug-stub}} |
{{nervous-system-drug-stub}} |