Bopindolol: Difference between revisions

Page 1
Page 2
Content deleted Content added
Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEMBL', 'KEGG', 'CAS_number').
mNo edit summary
 
(23 intermediate revisions by 21 users not shown)
Line 1: Line 1:
{{Short description|Chemical compound}}
{{Drugbox
{{Drugbox
| Verifiedfields = changed
| Verifiedfields = changed
| verifiedrevid = 444808722
| verifiedrevid = 459981210
| IUPAC_name = (''RS'')-1-(''tert''-butylamino)-3-[(2-methyl-1''H''-indol-4-yl)oxy]propan-2-yl benzoate
| IUPAC_name = (''RS'')-1-(''tert''-butylamino)-3-[(2-methyl-1''H''-indol-4-yl)oxy]propan-2-yl benzoate
| image = Bopindolol.png
| image = Bopindolol.svg


<!--Clinical data-->
<!--Clinical data-->
Line 26: Line 27:


<!--Identifiers-->
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = <!-- blanked - oldvalue: 69010-88-4 -->
| CAS_number = 62658-63-3
| ATC_prefix = C07
| ATC_prefix = C07
| ATC_suffix = AA17
| ATC_suffix = AA17
| ATC_supplemental =
| ATC_supplemental =
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 357995
| ChEMBL = 357995
| PubChem = 44112
| PubChem = 44112
Line 37: Line 39:
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 40146
| ChemSpiderID = 40146
| ChEBI = 76749
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = KT304VZO57
| UNII = KT304VZO57
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = <!-- blanked - oldvalue: D07537 -->
| KEGG = D07537

<!--Chemical data-->
| chemical_formula =
| chemical_formula =
| C=23 | H=28 | N=2 | O=3
| C=23 | H=28 | N=2 | O=3
| molecular_weight = 380.48 g/mol
| smiles = CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3
| smiles = CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
Line 51: Line 55:
}}
}}


'''Bopindolol''' ([[International Nonproprietary Name|INN]]) is a [[beta blocker]]. It is an [[ester]] which acts as a [[prodrug]] for [[pindolol]].
'''Bopindolol''' ([[International Nonproprietary Name|INN]]) is a [[beta blocker]]. It is an [[ester]] which acts as a [[prodrug]] for its [[active metabolite]] 4-(3-''t''-butylamino-2-hydroxypropoxy)-2-methylindole.<ref>{{cite journal | title=Bopindolol: pharmacological basis and clinical implications | vauthors=Nagatomo T, Hosohata Y, Ohnuki T, Nakamura T, Hattori K, Suzuki J, Ishiguro M | journal=Cardiovascular Drug Reviews |date=Spring 2001 | volume=19 | issue=1 | pages=9–24 | doi=10.1111/j.1527-3466.2001.tb00180.x | pmid=11314603| doi-access=free }}</ref>


==See also==
* [[Pindolol]]


==References==
{{reflist}}
{{Beta blockers}}
{{Beta blockers}}


[[Category:Beta blockers]]
[[Category:Beta blockers]]
[[Category:Prodrugs]]
[[Category:Prodrugs]]
[[Category:Benzoates]]
[[Category:Benzoate esters]]
[[Category:Amines]]
[[Category:N-tert-butyl-phenoxypropanolamines]]
[[Category:Phenol ethers]]
[[Category:Indole ethers at the benzene ring]]
[[Category:Indoles]]


{{Amine-stub}}
{{Amine-stub}}
{{cardiovascular-drug-stub}}
{{cardiovascular-drug-stub}}

[[es:Bopindolol]]
[[it:Bopindololo]]
[[ru:Бопиндолол]]