Bopindolol: Difference between revisions
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Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEMBL', 'KEGG', 'CAS_number'). |
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{{Short description|Chemical compound}} |
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{{Drugbox |
{{Drugbox |
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| Verifiedfields = changed |
| Verifiedfields = changed |
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| verifiedrevid = |
| verifiedrevid = 459981210 |
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| IUPAC_name = (''RS'')-1-(''tert''-butylamino)-3-[(2-methyl-1''H''-indol-4-yl)oxy]propan-2-yl benzoate |
| IUPAC_name = (''RS'')-1-(''tert''-butylamino)-3-[(2-methyl-1''H''-indol-4-yl)oxy]propan-2-yl benzoate |
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| image = Bopindolol. |
| image = Bopindolol.svg |
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<!--Clinical data--> |
<!--Clinical data--> |
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<!--Identifiers--> |
<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct| |
| CAS_number_Ref = {{cascite|correct|CAS}} |
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| CAS_number = |
| CAS_number = 62658-63-3 |
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| ATC_prefix = C07 |
| ATC_prefix = C07 |
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| ATC_suffix = AA17 |
| ATC_suffix = AA17 |
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| ATC_supplemental = |
| ATC_supplemental = |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 357995 |
| ChEMBL = 357995 |
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| PubChem = 44112 |
| PubChem = 44112 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 40146 |
| ChemSpiderID = 40146 |
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| ChEBI = 76749 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = KT304VZO57 |
| UNII = KT304VZO57 |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
| KEGG_Ref = {{keggcite|changed|kegg}} |
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| KEGG = |
| KEGG = D07537 |
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<!--Chemical data--> |
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| chemical_formula = |
| chemical_formula = |
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| C=23 | H=28 | N=2 | O=3 |
| C=23 | H=28 | N=2 | O=3 |
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| molecular_weight = 380.48 g/mol |
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| smiles = CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3 |
| smiles = CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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}} |
}} |
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'''Bopindolol''' ([[International Nonproprietary Name|INN]]) is a [[beta blocker]]. It is an [[ester]] which acts as a [[prodrug]] for [[ |
'''Bopindolol''' ([[International Nonproprietary Name|INN]]) is a [[beta blocker]]. It is an [[ester]] which acts as a [[prodrug]] for its [[active metabolite]] 4-(3-''t''-butylamino-2-hydroxypropoxy)-2-methylindole.<ref>{{cite journal | title=Bopindolol: pharmacological basis and clinical implications | vauthors=Nagatomo T, Hosohata Y, Ohnuki T, Nakamura T, Hattori K, Suzuki J, Ishiguro M | journal=Cardiovascular Drug Reviews |date=Spring 2001 | volume=19 | issue=1 | pages=9–24 | doi=10.1111/j.1527-3466.2001.tb00180.x | pmid=11314603| doi-access=free }}</ref> |
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==See also== |
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* [[Pindolol]] |
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==References== |
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{{reflist}} |
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{{Beta blockers}} |
{{Beta blockers}} |
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[[Category:Beta blockers]] |
[[Category:Beta blockers]] |
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[[Category:Prodrugs]] |
[[Category:Prodrugs]] |
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[[Category: |
[[Category:Benzoate esters]] |
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[[Category: |
[[Category:N-tert-butyl-phenoxypropanolamines]] |
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[[Category: |
[[Category:Indole ethers at the benzene ring]] |
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[[Category:Indoles]] |
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{{Amine-stub}} |
{{Amine-stub}} |
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{{cardiovascular-drug-stub}} |
{{cardiovascular-drug-stub}} |
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[[es:Bopindolol]] |
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[[it:Bopindololo]] |
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[[ru:Бопиндолол]] |