Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Pirprofen: Difference between pages
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Saving copy of the {{drugbox}} taken from revid 456864037 of page Pirprofen for the Chem/Drugbox validation project (updated: 'CAS_number'). |
Added s2cid. Added the cs1 style template to denote Vancouver ("vanc") citation style, because references contain "vauthors" attribute to specify the list of authors. |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid [{{fullurl:Pirprofen|oldid=456864037}} 456864037] of page [[Pirprofen]] with values updated to verified values.}} |
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{{cs1 config|name-list-style=vanc}} |
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{{Drugbox |
{{Drugbox |
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| Verifiedfields = changed |
| Verifiedfields = changed |
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| Watchedfields = changed |
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| IUPAC_name = 2-[3-chloro-4-(2,5-dihydro-1''H''-pyrrol-1-yl)phenyl]propanoic acid |
| IUPAC_name = 2-[3-chloro-4-(2,5-dihydro-1''H''-pyrrol-1-yl)phenyl]propanoic acid |
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| image = Pirprofen.png |
| image = Pirprofen.png |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
| legal_status = |
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| routes_of_administration = |
| routes_of_administration = |
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<!--Pharmacokinetic data--> |
<!--Pharmacokinetic data--> |
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| metabolism = |
| metabolism = |
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| elimination_half-life = |
| elimination_half-life = |
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| excretion = |
| excretion = |
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<!--Identifiers--> |
<!--Identifiers--> |
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| CAS_number_Ref = {{cascite| |
| CAS_number_Ref = {{cascite|changed|??}} |
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| CAS_number = |
| CAS_number = 31793-07-4 |
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| ATC_prefix = M01 |
| ATC_prefix = M01 |
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| ATC_suffix = AE08 |
| ATC_suffix = AE08 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 33051 |
| ChemSpiderID = 33051 |
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| UNII_Ref = {{fdacite| |
| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = T7KN291890 |
| UNII = T7KN291890 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
| KEGG_Ref = {{keggcite|correct|kegg}} |
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<!--Chemical data--> |
<!--Chemical data--> |
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| C=13 | H=14 | Cl=1 | N=1 | O=2 |
| C=13 | H=14 | Cl=1 | N=1 | O=2 |
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| molecular_weight = 251.70876 g/mol |
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| smiles = O=C(O)C(c1cc(Cl)c(cc1)N2C/C=C\C2)C |
| smiles = O=C(O)C(c1cc(Cl)c(cc1)N2C/C=C\C2)C |
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| InChI = 1/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/h2-5,8-9H,6-7H2,1H3,(H,16,17) |
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| InChIKey = PIDSZXPFGCURGN-UHFFFAOYAP |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/h2-5,8-9H,6-7H2,1H3,(H,16,17) |
| StdInChI = 1S/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/h2-5,8-9H,6-7H2,1H3,(H,16,17) |
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| StdInChIKey = PIDSZXPFGCURGN-UHFFFAOYSA-N |
| StdInChIKey = PIDSZXPFGCURGN-UHFFFAOYSA-N |
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}} |
}} |
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'''Pirprofen''' was a [[nonsteroidal anti-inflammatory drug]] (NSAID)<ref name="Todd_1986">{{cite journal | vauthors = Todd PA, Beresford R | title = Pirprofen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy | journal = Drugs | volume = 32 | issue = 6 | pages = 509–37 | date = December 1986 | pmid = 3539573 | doi = 10.2165/00003495-198632060-00003 | s2cid = 195692709 }}</ref> that was brought to market by [[Ciba-Geigy]] in 1982 as a treatment for [[arthritis]] and pain. Its label was restricted after adverse events arose, including some cases of fatal liver toxicity.<ref name="Depla_1990">{{cite journal | vauthors = Depla AC, Vermeersch PH, van Gorp LH, Nadorp JH | title = Fatal acute liver failure associated with pirprofen. Report of a case and a review of the literature | journal = The Netherlands Journal of Medicine | volume = 37 | issue = 1–2 | pages = 32–6 | date = August 1990 | pmid = 2215831 | doi = | url = }}</ref> Ciba-Geigy voluntarily withdrew the drug from the market worldwide in 1990.<ref>WHO. [https://web.archive.org/web/20141108142051/http://apps.who.int/medicinedocs/en/d/Js16780e/ Consolidated List of Products - Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or Not Approved by Governments, Twelfth Issue - Pharmaceuticals]. United Nations - New York, 2005</ref>{{rp|223}} |
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==References== |
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{{Reflist}} |
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{{Anti-inflammatory and antirheumatic products}} |
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{{Prostanoidergics}} |
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[[Category:Propionic acids]] |
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[[Category:Hepatotoxins]] |
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[[Category:Nonsteroidal anti-inflammatory drugs]] |
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[[Category:Pyrrolines]] |
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[[Category:Chloroarenes]] |
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{{musculoskeletal-drug-stub}} |
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