Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Thonzonium bromide: Difference between pages

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Saving copy of the {{chembox}} taken from revid 430521151 of page Thonzonium_bromide for the Chem/Drugbox validation project (updated: 'ChEMBL', 'CASNo').
 
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid [{{fullurl:Thonzonium_bromide|oldid=430521151}} 430521151] of page [[Thonzonium_bromide]] with values updated to verified values.}}
{{Chembox
{{Chembox
| Verifiedfields = changed
⚫
| verifiedrevid = 430352696
| Watchedfields = changed
⚫
| verifiedrevid = 477863667
| ImageFile = Thonzonium bromide.svg
| ImageFile = Thonzonium bromide.svg
| ImageSize = 250px
| ImageSize = 250px
| IUPACName = ''N''-{2-[(4-Methoxybenzyl)(pyrimidin-2-yl)amino]ethyl}-''N'',''N''-dimethylhexadecan-1-aminium bromide
| PIN = ''N''-(2-<nowiki/>{[(4-Methoxyphenyl)methyl](pyrimidin-2-yl)amino}ethyl)-''N'',''N''-dimethylhexadecan-1-aminium bromide
| OtherNames =
| OtherNames =
| Section1 = {{Chembox Identifiers
|Section1={{Chembox Identifiers
| CASNo = <!-- blanked - oldvalue: 553-08-2 -->
| CASNo = 553-08-2
| CASNo_Ref = {{Cascite|correct|CAS}}
| CASNo_Ref = {{cascite|correct|CAS}}
| UNII_Ref = {{fdacite|correct|FDA}}
⚫
| PubChem = 11102
| UNII = JI2B19CR0R
⚫
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
⚫
| PubChem = 11102
⚫
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10631
| ChemSpiderID = 10631
| SMILES = [Br-].O(c1ccc(cc1)CN(c2ncccn2)CC[N+](CCCCCCCCCCCCCCCC)(C)C)C
| SMILES = [Br-].O(c1ccc(cc1)CN(c2ncccn2)CC[N+](CCCCCCCCCCCCCCCC)(C)C)C
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = <!-- blanked - oldvalue: 1200883 -->
| ChEMBL = 1200883
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI=1S/C32H55N4O.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27-36(2,3)28-26-35(32-33-24-19-25-34-32)29-30-20-22-31(37-4)23-21-30;/h19-25H,5-18,26-29H2,1-4H3;1H/q+1;/p-1
| StdInChI=1S/C32H55N4O.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27-36(2,3)28-26-35(32-33-24-19-25-34-32)29-30-20-22-31(37-4)23-21-30;/h19-25H,5-18,26-29H2,1-4H3;1H/q+1;/p-1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = WBWDWFZTSDZAIG-UHFFFAOYSA-M
| StdInChIKey = WBWDWFZTSDZAIG-UHFFFAOYSA-M
}}
}}
| Section2 = {{Chembox Properties
|Section2={{Chembox Properties
| C=32|H=55|Br=1|N=4|O=1
| C=32 | H=55 | Br=1 | N=4 | O=1
| Appearance =
| Appearance =
| Density =
| Density =
| MeltingPt =
| MeltingPt =
| BoilingPt =
| BoilingPt =
| Solubility =
| Solubility =
}}
}}
| Section3 = {{Chembox Hazards
|Section3={{Chembox Hazards
| MainHazards =
| MainHazards =
| FlashPt =
| FlashPt =
| Autoignition =
| AutoignitionPt =
}}
}}
}}
}}

'''Thonzonium bromide''' is a monocationic detergent.<ref>{{Cite web |title=Thonzonium bromide |url=http://www.cdek.liu.edu/api/109493/ |access-date=2023-01-02 |website=[[Long Island University]]}}</ref> A solution of it is thus a [[surfactant]] and a [[detergent]] that promotes tissue contact by dispersion and penetration of the cellular debris and exudate of the containing solution.<ref>{{Cite journal |date=2009-12-15 |title=Otic Antibiotics Review 2009 |url=https://www.medicaid.nv.gov/Downloads/provider/NVRx_DCR_20100624_Otic_Antibiotics.pdf |url-status=live |format=PDF |journal=Otic Antibiotics Review |volume=6 |issue=1 |pages=11 |archive-url=https://web.archive.org/web/20230103030748/https://www.medicaid.nv.gov/Downloads/provider/NVRx_DCR_20100624_Otic_Antibiotics.pdf |archive-date=2023-01-03 |access-date=2023-01-03 |via=[[Nevada Department of Health and Human Services]]}}</ref>

It is used in cortisporin-TC ear drops to help penetration of active ingredients through cellular debris for its antibacterial action.<ref>{{Cite web |date=2022-10-15 |title=Cortisporin-TC: Indications, Side Effects, Warnings |url=https://www.drugs.com/cdi/cortisporin-tc.html |url-status=live |archive-url=https://web.archive.org/web/20230103031059/https://www.drugs.com/cdi/cortisporin-tc.html |archive-date=2023-01-03 |access-date=2023-01-03 |website=[[Drugs.com]] |language=en}}</ref><ref>{{Cite web |year=2019 |title=CORTISPORIN-TC- colistin sulfate, neomycin sulfate, thonzonium bromide and hydrocortisone acetate suspension |url=https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050356s059lbl.pdf |url-status=live |archive-url=https://web.archive.org/web/20230103031351/https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050356s059lbl.pdf |archive-date=2023-01-03 |access-date=2023-01-02 |website=[[Food and Drug Administration]] |format=PDF}}</ref>

==References==
{{Reflist|2}}

{{Xenobiotic-sensing receptor modulators}}

[[Category:Aminopyrimidines]]
[[Category:Quaternary ammonium compounds]]
[[Category:Cationic surfactants]]
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