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Gene therapy is a medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological...172 KB (17,769 words) - 01:31, 8 May 2024- This article contains a list of commercially available gene therapies. Alipogene tiparvovec (Glybera): AAV-based treatment for lipoprotein lipase deficiency...10 KB (792 words) - 10:27, 12 December 2023
- somatic cell line, and thus its host organism. Gene delivery is a necessary step in gene therapy for the introduction or silencing of a gene to promote a therapeutic...24 KB (2,869 words) - 16:15, 28 August 2023
- for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys suggesting an imminent gene therapy in humans...18 KB (2,336 words) - 18:26, 1 May 2024
Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods...36 KB (4,918 words) - 09:36, 27 February 2024
Lentiviral vectors in gene therapy is a method by which genes can be inserted, modified, or deleted in organisms using lentiviruses. Lentiviruses are...29 KB (3,448 words) - 01:15, 19 February 2024- striatum is another alternative gene therapy. This therapy consists on transferring the TH and GTP cyclohydrolase 1 genes into the MSNs because the endogenous...14 KB (1,819 words) - 05:17, 18 December 2023
- as infectious diseases and neurodegenerative disorders. Gene silencing is often considered the same as gene knockdown. When genes are silenced, their expression...48 KB (5,608 words) - 02:20, 6 February 2024
categories: caretaker genes, gatekeeper genes, and more recently landscaper genes. Caretaker genes ensure stability of the genome via DNA repair and subsequently...30 KB (3,406 words) - 23:46, 11 April 2024- introduction (through gene therapy) of suicide genes is a potential way of treating cancer or other proliferative diseases. Suicide genes form the basis of...16 KB (2,163 words) - 19:30, 6 April 2024
- Gene therapy for osteoarthritis is the application of gene therapy to treat osteoarthritis (OA). Unlike pharmacological treatments which are administered...45 KB (5,295 words) - 21:47, 9 February 2024
modulate gene expression by targeting dCas9-repressors or activators toward promoter or transcriptional start sites of target genes. For repressing genes Cas9...150 KB (17,439 words) - 13:58, 7 May 2024- zebrafish, and mice. In mice, gene knockouts are commonly used to study the function of specific genes in development, physiology, and cancer research...21 KB (2,524 words) - 18:03, 29 April 2024
Gene doping is the hypothetical non-therapeutic use of gene therapy by athletes in order to improve their performance in those sporting events which prohibit...32 KB (3,911 words) - 00:09, 27 February 2024
functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression, DNA is first copied into RNA. RNA...112 KB (12,720 words) - 21:30, 18 May 2024- Novartis Gene Therapies, until 2020 known as AveXis, is a biotechnology company that develops treatments for rare neurological genetic disorders. It was...9 KB (767 words) - 16:35, 12 May 2024
- Retinal gene therapy holds a promise in treating different forms of non-inherited and inherited blindness. In 2008, three independent research groups...37 KB (4,699 words) - 05:18, 18 December 2023
Sio Gene Therapies, Inc. (formerly known as Axovant Gene Therapies) was a clinical-stage pharmaceutical company that developed gene therapies to treat...16 KB (1,263 words) - 20:54, 11 May 2024
genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences...12 KB (1,433 words) - 19:11, 29 April 2024
rate and these genes can be used as a reference point in experiments to measure the expression rates of other genes. A facultative gene is a gene only...81 KB (9,242 words) - 18:03, 29 April 2024
- on: gene therapy Wikipedia gene therapy (countable and uncountable, plural gene therapies) Any of several therapies involving the insertion of genes into
- Genetics is the study of genes, heredity, and genetic variation in living organisms. Humanity should study the foundations of heredity. But this will be
- efficacy of the technique, preventing it to be considered as a future gene replacement therapy. A new CRISPR version developed by Gaudelli et al. reduced the
- Gene therapy is an experimental technique that uses genes to treat or prevent diseases. Genes are specific sequences of bases that encode instructions