Talk:Wolff–Chaikoff effect: Difference between revisions
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→Jodbasedow phenomenon: note 1948 orig paper is fn 4 of article |
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http://www.jbc.org/cgi/reprint/174/2/555 <small>—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/84.45.158.52|84.45.158.52]] ([[User talk:84.45.158.52|talk]]) 23:19, 10 January 2008 (UTC)</small><!-- Template:UnsignedIP --> <!--Autosigned by SineBot--> |
http://www.jbc.org/cgi/reprint/174/2/555 <small>—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/84.45.158.52|84.45.158.52]] ([[User talk:84.45.158.52|talk]]) 23:19, 10 January 2008 (UTC)</small><!-- Template:UnsignedIP --> <!--Autosigned by SineBot--> |
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:::The above 1948 original paper is now article footnote 4 (as of 30 Dec 2015). |
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==Junk Science== |
==Junk Science== |
Revision as of 20:03, 30 December 2015
Medicine Start‑class Low‑importance | ||||||||||
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Jodbasedow phenomenon
I believe what you describe is the Jodbasedow phenomenon. The Wolff-Chaikoff effect is the normal inhibition of iodine organification and hormone formation once the maximum level has been reached. It is the "shut-off switch" for the system. With the Jodbasedow phenomenon, the shutoff is not working and iodine continues to be transported across the membrane, organified and hormone made, resulting in an iodine-induced hypothyroidism.
--Name8318 02:37, 20 July 2007 (UTC)
Suggest this reference should be considered.
Plasma Inorganic Iodide as a Homeostatic Regulator of Thyroid Function.
J. Biol. Chem. Wolff and Chaikoff 174 (2): 555
The paper is available for free download.
http://www.jbc.org/cgi/reprint/174/2/555 —Preceding unsigned comment added by 84.45.158.52 (talk) 23:19, 10 January 2008 (UTC)
- The above 1948 original paper is now article footnote 4 (as of 30 Dec 2015).
Junk Science
This is junk science. Google "Wolff–Chaikoff effect" for details. 75.0.9.162 (talk) 20:12, 27 September 2013 (UTC)
- Controversy is welcome. Are there some peer-reviewed sources you could references or link here?