3-Hydroxypentanoic acid
Appearance
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Names | |
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IUPAC name
3-Hydroxypentanoic acid
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Other names
3-Hydroxyvalerate
3-Hydroxy valeric acid beta-Hydroxyvaleric acid beta-Hydroxypentanoate | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.123.761 |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C5H10O3 | |
Molar mass | 118.13 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3-Hydroxypentanoic acid, or beta-hydroxypentanoate is a 5-carbon ketone body. It is made from odd carbon fatty acids in the liver and rapidly enters the brain. As opposed to 4-carbon ketone bodies, 3-hydroxypentanoic acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates. The triglyceride triheptanoin is used clinically to produce beta-hydroxypentanoate.[1]
References
- ^ Renée P. Kinman, Takhar Kasumov, Kathryn A. Jobbins, Katherine R. Thomas, Jillian Adams, Lisa N. Brunengraber, Gerd Kutz, Wolf-Ulrich Brewer, Charles R. Roe, and Henri Brunengraber (2006). "Parenteral and Enteral Metabolism of Anaplerotic Triheptanoin in Normal Rats". Am J Physiol Endocrinol Metab. 291 (4): E860–E866. doi:10.1152/ajpendo.00366.2005. PMID 16705058.
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