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Durcupan

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Durcupan is a water-soluble epoxy resin produced by the Fluka subsidiary of Sigma-Aldrich. It is commonly used for embedding electron microscope samples in plastic so they may be sectioned (sliced thin) with a microtome and then imaged. [1] [2] [3]

Durcupan is notable for refractive index nD20 of 1.654, which is a very high value for epoxy resins.[4]

References

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  1. ^ Stäubli, W. (1963). "A new embedding technique for electron microscopy, combining a water-soluble epoxy resin (Durcupan) with water-insoluble Araldite" (PDF). The Journal of Cell Biology. 16 (1). Rockefeller Univ Press: 197–201. doi:10.1083/jcb.16.1.197. PMC 2106182. PMID 13978678.
  2. ^ Kushida, H. (1963). "A Modification of the Water-miscible Epoxy Resin "Durcupan" Embedding Method for Ultrathin Sectioning". Journal of Electron Microscopy. 12 (1). Japan Society Microscopy: 72–73. doi:10.1093/oxfordjournals.jmicro.a049375. Archived from the original on 2013-04-15.
  3. ^ "Durcupan recipe". Cold Spring Harbor Protocols. 2011: pdb.rec12381. 2011. doi:10.1101/pdb.rec12381.
  4. ^ Punge, A. (2009). Polymer embedding for ultrathin slicing and optical nanoscopy of thick fluorescent samples. Dissertation zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultäten der Georg-August-Universität zu Göttingen. pp. 34–35. Archived from the original on 2017-06-22.