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PGG-glucan

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This is an old revision of this page, as edited by Malcolmxl5 (talk | contribs) at 15:35, 31 July 2022 (Adding short description: "Immunomodulator"). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Poly-[1-6]--D-glucopyranosyl-[1-3]--D-glucopyranose glucan (PGG glucan, proprietary name Betafectin)[1] is an anti-infective agent and a form or type of beta-glucan.

Betafectin is a PGG-glucan, a novel β-(1,6) branched β-(1,3) glucan, purified from the cell walls of Saccharomyces cerevisiae.[2]

It is a macrophage-specific immunomodulator.

References

  1. ^ Prophylactic Anti-Infective Activity of Poly-[1-6]-beta -D-Glucopyranosyl-[1-3]-beta -D-Glucopyranose Glucan in a Guinea Pig Model of Staphylococcal Wound Infection - Kernodle et al. 42 (3): 545 - Antimicrobial Agents and Chemotherapy
  2. ^ Effect on progenitor blood cells
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