Jump to content

CM-4620

Add links
From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Entranced98 (talk | contribs) at 22:45, 29 January 2023 (Importing Wikidata short description: "Chemical compound"). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

CM-4620
Identifiers
  • N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-2-fluoro-6-methylbenzamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC19H11ClF3N3O3
Molar mass421.8 g·mol−1
3D model (JSmol)
  • CC1=C(C(=CC=C1)F)C(=O)NC2=NC=C(N=C2)C3=CC4=C(C=C3Cl)OC(O4)(F)F
  • InChI=1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27)
  • Key:QQMKTHUGOQDEIL-UHFFFAOYSA-N

CM-4620 is a drug which acts as a selective inhibitor of the calcium channel ORAI1. It has antiinflammatory effects and is being researched for the treatment of pancreatitis.[1]

References

  1. ^ Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, et al. (June 2019). "The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis". The Journal of Physiology. 597 (12): 3085–3105. doi:10.1113/JP277856. PMC 6582954. PMID 31050811.


Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=CM-4620&oldid=1136349501"