Adiphenine
Appearance
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Names | |
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Preferred IUPAC name
2-(Diethylamino)ethyl diphenylacetate | |
Other names
Diphacil
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.000.545 |
EC Number |
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KEGG | |
MeSH | C084829 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H25NO2 | |
Molar mass | 311.425 g·mol−1 |
Melting point | 112–114 °C (234–237 °F; 385–387 K) |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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290 mg/kg (mouse; intraperitoneal) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Adiphenine is an inhibitor of nicotinic receptors.[1]
Pharmacology and Biochemistry
See also
References
- ^ Spitzmaul, G; Gumilar, F; Dilger, JP; Bouzat, C (2009). "The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms". British Journal of Pharmacology. 157 (5): 804–17. doi:10.1111/j.1476-5381.2009.00214.x. PMC 2721265. PMID 19422391.