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Bronidox

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Bronidox
Names
Preferred IUPAC name
5-Bromo-5-nitro-1,3-dioxane
Other names
5-Bromo-5-nitro-m-dioxane
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.045.441 Edit this at Wikidata
EC Number
  • 250-001-7
UNII
  • InChI=1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 checkY
    Key: XVBRCOKDZVQYAY-UHFFFAOYSA-N checkY
  • InChI=1/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2
    Key: XVBRCOKDZVQYAY-UHFFFAOYAG
  • O=[N+]([O-])C1(Br)COCOC1
Properties
C4H6BrNO4
Molar mass 211.999 g·mol−1
Appearance White crystalline powder
Melting point 60 °C (140 °F; 333 K)[1]
58.5−62 °C[2]
insoluble
Hazards
GHS labelling:
GHS05: CorrosiveGHS07: Exclamation markGHS09: Environmental hazard
Danger
H302, H314, H315, H317, H410
P260, P261, P264, P270, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P332+P313, P333+P313, P362, P363, P391, P405, P501
Lethal dose or concentration (LD, LC):
590 mg/kg (mouse, oral)
455 mg/kg (rat, oral)
31 mg/kg (rat, ipr.)
2500 µg (mouse, skin)
2500 µg (rat, skin)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound.

Bronidox causes inhibition of enzyme activity in bacteria.[3]

Bronidox is corrosive to metals.[4]

Uses

See also

References

  1. ^ 5-BROMO-5-NITRO-1,3-DIOXANE Archived March 3, 2016, at the Wayback Machine, chemicalland21.com
  2. ^ "Bronidox, Product Information Sheet" (PDF). Archived from the original (PDF) on September 29, 2007. Retrieved March 19, 2006.
  3. ^ Ghannoum M, Thomson M, Bowman W, Al-Khalil S (1986). "Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox)". Folia Microbiol. (Praha). 31 (1): 19–31. doi:10.1007/BF02928676. PMID 3082729. S2CID 23920602.
  4. ^ http://www.products.cognis.com/COGNIS/prodleaf.nsf/(SBU_Catalog)/FFAD30C61B67EFEB41256B4100427DD1/$File/BRONIDOX_r_L_5_E.pdf [dead link]
  5. ^ [1] Archived December 21, 2004, at the Wayback Machine