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List of phylogenetic tree visualization software

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OneZoom

This list of phylogenetic tree viewing software is a compilation of software tools and web portals used in visualizing phylogenetic trees.

Online software

Name Description License
Annotations QUick Analysis for PhylOgeNY (Aquapony[1]) Javascript tree viewer for Beast CeCILL
ETE toolkit Tree Viewer[2] an online tool for phylogenetic tree view (newick format) that allows multiple sequence alignments to be shown together with the trees (fasta format)
EvolView[3] an online tool for visualizing, annotating and managing phylogenetic trees
IcyTree[4] Client-side Javascript SVG viewer for annotated rooted trees. Also supports phylogenetic networks
Iroki[5] Automatic customization and visualization of phylogenetic trees
iTOL - interactive Tree Of Life[6] annotate trees with various types of data and export to various graphical formats; scriptable through a batch interface
Microreact[7] Link, visualise and explore sequence and meta-data using phylogenetic trees, maps and timelines
OneZoom[8] uses IFIG (Interactive Fractal Inspired Graphs) to display phylogenetic trees which can be zoomed in on to increase detail
Phylo.io[9] View and compare up to 2 trees side by side with interactive HTML5 visualisations
PhyloExplorer[10] a tool to facilitate assessment and management of phylogenetic tree collections. Given an input collection of rooted trees, PhyloExplorer provides facilities for obtaining statistics describing the collection, correcting invalid taxon names, extracting taxonomically relevant parts of the collection using a dedicated query language, and identifying related trees in the TreeBASE database.
PHYLOViZ Online[11] Web-based tool for visualization, phylogenetic inference, analysis and sharing of minimum spanning trees
PhyloWidget[12] view, edit, and publish phylogenetic trees online; interfaces with databases
PRESTO[13] a Phylogenetic tReE viSualisaTion.
Taxonium[14] web-based tool for exploration of very large trees including those with millions of nodes, with search and metadata coloring. When provided with a mutation-annotated tree, it illustrates mutations on the tree and displays final genotypes.
T-REX (Webserver)[15] Tree inference and visualization (hierarchical, radial and axial tree views), Horizontal gene transfer detection and HGT network visualization
TidyTree[16] A client-side HTML5/SVG Phylogenetic Tree Renderer, based on D3.js
TreeVector[17] scalable, interactive, phylogenetic trees for the web, produces dynamic SVG or PNG output, implemented in Java

Desktop software

Name Description OS1 Citation
ARB An integrated software environment for tree visualisation and annotation LM [18]
Archaeopteryx Java tree viewer and editor (used to be ATV) [19]
BioNumerics Universal platform for the management, storage and analysis of all types of biological data, including tree and network inference of sequence data W [20]
Bio::Phylo A collection of Perl modules for manipulating and visualizing phylogenetic data. Bio::Philo is one part of a comprehensive suite of Perl biology tools All [21]
Dendroscope An interactive viewer for large phylogenetic trees and networks All [22]
DensiTree A viewer capable of viewing multiple overlaid trees. All [23]
FigTree Simple Java tree viewer able to read newick and nexus tree files. Can be used to color branches and produce vector artwork. All [24]
JEvTrace A multivalent browser for sequence alignment, phylogeny, and structure. Performs an interactive Evolutionary Trace[25] and other phylogeny-inspired analysis. All [26]
MEGA Software for statistical analysis of molecular evolution. It includes different tree visualization features All [27]
MultiDendrograms Interactive open-source application to calculate and plot phylogenetic trees All [28]
PHYLOViZ Phylogenetic inference and data visualization for allelic/SNP sequences profiles using Minimum Spanning Trees All [29]
SplitsTree Software for viewing trees, cladograms, NeighborNets, and other graphs All [30]
TreeDyn Open-source software for tree manipulation and annotation allowing incorporation of meta information All [31]
Treevolution Open-source tool for circular visualization with section and ring distortion and several other features such as branch clustering and pruning All [32]
TreeGraph 2 Open-source tree editor with numerous editing and formatting operations including combining different phylogenetic analyses All [33]
TreeView Treeviewing software All [34][35]
UGENE An opensource visual interface for Phylip 3.6 package All [36]
TreeViewer Flexible, modular software to visualise and manipulate phylogenetic trees All [37]

1 "All" refers to Microsoft Windows, Apple OSX and Linux; L=Linux, M=Apple Mac, W=Microsoft Windows

Libraries

Name Language Description Citation
ggtree R An R package for tree visualization and annotation with grammar of graphics supported [38]
jsPhyloSVG Javascript open-source javascript library for rendering highly-extensible, customizable phylogenetic trees; used for Elsevier's interactive trees [39][40]
PhyD3 Javascript interactive phylogenetic tree visualization with numerical annotation graphs, with SVG or PNG output, implemented in D3.js [41]
phylotree.js Javascript phylotree.js is a library that extends the popular data visualization framework D3.js, and is suitable for building JavaScript applications where users can view and interact with phylogenetic trees [42]
PhyloPlots.jl Julia PhyloPlots.jl is a julia package for plotting phylogenetic trees and networks, integrated with PhyloNetworks.jl [43]
Phytools R Phylogenetic Tools for Comparative Biology (and Other Things) based in R [44]
toytree Python Toytree: A minimalist tree visualization and manipulation library for Python [45]

See also

References

  1. ^ Cazaux B, Castel G, Rivals E (September 2019). "AQUAPONY: visualization and interpretation of phylogeographic information on phylogenetic trees". Bioinformatics. 35 (17): 3163–3165. doi:10.1093/bioinformatics/btz011. PMID 30649190. Archived from the original on 2019-02-03.
  2. ^ Huerta-Cepas J, Dopazo J, Gabaldón T (January 2010). "ETE: a python Environment for Tree Exploration". BMC Bioinformatics. 11: 24. doi:10.1186/1471-2105-11-24. PMC 2820433. PMID 20070885.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  3. ^ Zhang H, Gao S, Lercher MJ, Hu S, Chen WH (July 2012). "EvolView, an online tool for visualizing, annotating and managing phylogenetic trees". Nucleic Acids Research. 40 (Web Server issue): W569–72. doi:10.1093/nar/gks576. PMC 3394307. PMID 22695796.
  4. ^ Vaughan TG (August 2017). "IcyTree: rapid browser-based visualization for phylogenetic trees and networks". Bioinformatics. 33 (15): 2392–2394. doi:10.1093/bioinformatics/btx155. PMC 5860111. PMID 28407035.
  5. ^ Moore RM, Harrison AO, McAllister SM, Polson SW, Wommack KE (February 2020). "Iroki: automatic customization and visualization of phylogenetic trees". PeerJ. 8 (e8584): e8584. doi:10.7717/peerj.8584. PMC 7049256. PMID 32149022.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  6. ^ Letunic I, Bork P (January 2007). "Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation" (PDF). Bioinformatics. 23 (1): 127–8. doi:10.1093/bioinformatics/btl529. PMID 17050570.
  7. ^ Argimón S, Abudahab K, Goater RJ, Fedosejev A, Bhai J, Glasner C, et al. (November 2016). "Microreact: visualizing and sharing data for genomic epidemiology and phylogeography". Microbial Genomics. 2 (11): e000093. doi:10.1099/mgen.0.000093. PMC 5320705. PMID 28348833.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  8. ^ Rosindell J, Harmon LJ (2012). "OneZoom: a fractal explorer for the tree of life". PLOS Biology. 10 (10): e1001406. doi:10.1371/journal.pbio.1001406. PMC 3472976. PMID 23091419.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  9. ^ Robinson O, Dylus D, Dessimoz C (August 2016). "Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web". Molecular Biology and Evolution. 33 (8): 2163–6. arXiv:1602.04258. Bibcode:2016arXiv160204258R. doi:10.1093/molbev/msw080. PMC 4948708. PMID 27189561.
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  11. ^ Ribeiro-Gonçalves B, Francisco AP, Vaz C, Ramirez M, Carriço JA (July 2016). "PHYLOViZ Online: web-based tool for visualization, phylogenetic inference, analysis and sharing of minimum spanning trees". Nucleic Acids Research. 44 (W1): W246–51. doi:10.1093/nar/gkw359. PMC 4987911. PMID 27131357.
  12. ^ Jordan GE, Piel WH (July 2008). "PhyloWidget: web-based visualizations for the tree of life". Bioinformatics. 24 (14): 1641–2. doi:10.1093/bioinformatics/btn235. PMID 18487241.
  13. ^ Guindon, Stéphane; Gascuel, Olivier (2003-10-01). "A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood". Systematic Biology. 52 (5): 696–704. doi:10.1080/10635150390235520. ISSN 1063-5157. PMID 14530136. S2CID 13857323.
  14. ^ Sanderson (2021). "Taxonium".
  15. ^ Boc A, Diallo AB, Makarenkov V (July 2012). "T-REX: a web server for inferring, validating and visualizing phylogenetic trees and networks". Nucleic Acids Research. 40 (Web Server issue): W573–9. doi:10.1093/nar/gks485. PMC 3394261. PMID 22675075.
  16. ^ Boyles A (2019). "TidyTree: Uncompromisingly Flexible Phylogenetic Trees". CDC.
  17. ^ Pethica R, Barker G, Kovacs T, Gough J (January 2010). "TreeVector: scalable, interactive, phylogenetic trees for the web". PLOS ONE. 5 (1): e8934. Bibcode:2010PLoSO...5.8934P. doi:10.1371/journal.pone.0008934. PMC 2812488. PMID 20126613.
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  19. ^ Zmasek CM, Eddy SR (April 2001). "ATV: display and manipulation of annotated phylogenetic trees". Bioinformatics. 17 (4): 383–4. doi:10.1093/bioinformatics/17.4.383. PMID 11301314.
  20. ^ BioNumerics protocols used by Pulsenet Archived December 6, 2011, at the Wayback Machine
  21. ^ Vos RA, Caravas J, Hartmann K, Jensen MA, Miller C (February 2011). "BIO::Phylo-phyloinformatic analysis using perl". BMC Bioinformatics. 12: 63. doi:10.1186/1471-2105-12-63. PMC 3056726. PMID 21352572.{{cite journal}}: CS1 maint: unflagged free DOI (link)
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  23. ^ Bouckaert R, Heled J (2014-12-08). "DensiTree 2: Seeing Trees Through the Forest". bioRxiv 10.1101/012401.
  24. ^ Rambaut A. 2018. FigTree 1.4.4 github.com accessed 17 April 2018
  25. ^ Lichtarge O, Bourne HR, Cohen FE (March 1996). "An evolutionary trace method defines binding surfaces common to protein families". Journal of Molecular Biology. 257 (2): 342–358. doi:10.1006/jmbi.1996.0167. PMID 8609628.
  26. ^ Joachimiak MP, Cohen FE (2002). "JEvTrace: refinement and variations of the evolutionary trace in JAVA". Genome Biology. 3 (12): RESEARCH0077. doi:10.1186/gb-2002-3-12-research0077. PMC 151179. PMID 12537566.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  27. ^ Kumar S, Stecher G, Li M, Knyaz C, Tamura K (June 2018). "MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms". Molecular Biology and Evolution. 35 (6): 1547–1549. doi:10.1093/molbev/msy096. PMC 5967553. PMID 29722887.
  28. ^ Fernández A, Gómez S (2008). "Solving Non-uniqueness in Agglomerative Hierarchical Clustering Using Multidendrograms". Journal of Classification. 25 (1): 43–65. arXiv:cs/0608049. doi:10.1007/s00357-008-9004-x. S2CID 434036.
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  32. ^ Santamaría R, Therón R (August 2009). "Treevolution: visual analysis of phylogenetic trees". Bioinformatics. 25 (15): 1970–1. doi:10.1093/bioinformatics/btp333. PMID 19470585.
  33. ^ Stöver BC, Müller KF (January 2010). "TreeGraph 2: combining and visualizing evidence from different phylogenetic analyses". BMC Bioinformatics. 11: 7. doi:10.1186/1471-2105-11-7. PMC 2806359. PMID 20051126.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  34. ^ "Publication Analysis 1996-2006 Evolutionary Biology" (PDF). Archived from the original (PDF) on 2015-02-14. Retrieved 2008-10-22.
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  37. ^ Bianchini, G; Sánchez-Baracaldo, P (2023). "TreeViewer Version 2.1.0". doi:10.5281/zenodo.7768343.
  38. ^ Yu G, Smith DK, Zhu H, Guan Y, Lam TT (January 1, 2017). "ggtree: an R package for visualization and annotation of phylogenetic trees with their covariates and other associated data". Methods in Ecology and Evolution. 8 (1): 28–36. doi:10.1111/2041-210X.12628. S2CID 63705866.
  39. ^ interactive-phylogenetic-treeswww.elsevier.com Archived 2017-05-31 at the Wayback Machine
  40. ^ Smits SA, Ouverney CC (August 2010). Poon AF (ed.). "jsPhyloSVG: a javascript library for visualizing interactive and vector-based phylogenetic trees on the web". PLOS ONE. 5 (8): e12267. Bibcode:2010PLoSO...512267S. doi:10.1371/journal.pone.0012267. PMC 2923619. PMID 20805892.
  41. ^ Kreft L, Botzki A, Coppens F, Vandepoele K, Van Bel M (September 2017). "PhyD3: a phylogenetic tree viewer with extended phyloXML support for functional genomics data visualization". Bioinformatics. 33 (18): 2946–2947. doi:10.1093/bioinformatics/btx324. PMID 28525531.
  42. ^ Shank SD, Weaver S, Kosakovsky Pond SL (July 2018). "phylotree.js - a JavaScript library for application development and interactive data visualization in phylogenetics". BMC Bioinformatics. 19 (1): 276. doi:10.1186/s12859-018-2283-2. PMC 6060545. PMID 30045713.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  43. ^ Solís-Lemus C, Bastide P, Ané C (2017). "PhyloNetworks: A Package for phylogenetic networks". Molecular Biology and Evolution. 34 (12): 3292–3298. doi:10.1093/molbev/msx235. PMID 28961984.
  44. ^ Revell, LJ (2012). "phytools: An R package for phylogenetic comparative biology (and other things)". Methods Ecol. Evol. 3 (2): 217–223. doi:10.1111/j.2041-210X.2011.00169.x. S2CID 32670711.
  45. ^ Eaton, DAR (2019). "Toytree: A minimalist tree visualization and manipulation library for Python". Methods Ecol. Evol. 11 (1): 187–191. doi:10.1111/2041-210X.13313.
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