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Michaelis–Gutmann bodies

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Micrograph showing Michaelis-Gutmann bodies. H&E stain.

Michaelis–Gutmann bodies (M-G bodies) are concentrically layered basophilic inclusions found in the urinary tract. They are 2 to 10 μm in diameter, and are thought to represent remnants of phagosomes mineralized by iron and calcium deposits.

M-G bodies are a pathognomonic feature of malakoplakia, an inflammatory condition that affects the genitourinary tract. They were discovered in 1902 by Leonor Michaelis and Carl Gutmann.

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