5'-Methoxyhydnocarpin
Appearance
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IUPAC name
5,7-Dihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydro-1,4-benzodioxin-7-yl]chromen-4-one
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Other names
5′-MHC
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
KEGG | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C26H22O10 | |
Molar mass | 494.452 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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5'-Methoxyhydnocarpin (5′-MHC) is a chemical compound that has been isolated from Berberis[1] and Hydnocarpus wightianus.[2]
5′-MHC potentiates the antimicrobial effect of berberine in vitro.[1]
References
- ^ a b Stermitz, F. R.; Lorenz, P; Tawara, J. N.; Zenewicz, L. A.; Lewis, K. (February 15, 2000). "Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor". Proceedings of the National Academy of Sciences. 97 (4). National Academy of Sciences: 1433–1437. Bibcode:2000PNAS...97.1433S. doi:10.1073/pnas.030540597. ISSN 1091-6490. PMC 26451. PMID 10677479.
- ^ Williams, Cheryll (2013). Medicinal Plants in Australia Volume 4: An Antipodean Apothecary. Rosenberg Publishing. p. 171. ISBN 9781925078084.