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Myoblast city

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Myoblast city
Identifiers
OrganismDrosophila melanogaster
Symbolmbc
UniProtQ9VCH4
Search for
StructuresSwiss-model
DomainsInterPro

Myoblast city (Mbc[1]) is the Drosophila melanogaster ortholog of the mammalian protein Dock180.[2] Mutant mbc embryos exhibit defects in dorsal closure, cytoskeletal organization, myogenesis, and neural development.[2][3]

References

  1. ^ "FlyBase Gene Report:Dmel\mbc". FlyBase Consortium. Retrieved February 25, 2009.
  2. ^ a b Erickson MR, Galletta BJ, Abmayr SM (August 1997). "Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization". J. Cell Biol. 138 (3): 589–603. doi:10.1083/jcb.138.3.589. PMC 2141626. PMID 9245788.
  3. ^ Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J (November 1998). "Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes". Genes Dev. 12 (21): 3337–42. doi:10.1101/gad.12.21.3337. PMC 317223. PMID 9808621.


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